Furosemide
CHEBI:CHEBI_47426
Definition
A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.
Chemical Information
- Molecular Formula
- C12H11ClN2O5S
- Molecular Mass
- 330.74400
- Charge
- 0
- SMILES
- NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccco2)cc1Cl
- InChI
- InChI=1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19)
- InChIKey
- ZZUFCTLCJUWOSV-UHFFFAOYSA-N
Alternative Names
- 2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid
- 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid
- 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid
- 4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid
- 4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid
- Frusemide
- Furosemide
- Lasix (TN)
Drug Classification
-
sulfonamideView Class →
CHEBI:35358
-
furansView Class →
CHEBI:24129
-
chlorobenzoic acidView Class →
CHEBI:23134
-
t227469
-
t227551
-
t227951
-
t227964
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 4603
- oboInOwl#hasDbXref
- Wikipedia:Furosemide
- core#notation
- CHEBI:47426
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- product_ndc
- 66326-401
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- dosage_form
- INJECTION, SOLUTION
- labeler_name
- Curia India Private Limited
- application_number
- ANDA070433
- route
- INTRAVENOUS
- package_ndc
- 63415-0029-0
- spl_id
- f7d4f744-9479-4688-b177-86801fed3245
- package_description
- 10 kg in 1 DRUM (66326-401-04)
- listing_expiration_date
- 20241231
- marketing_start_date
- 20000712
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 4603
- oboInOwl#hasDbXref
- Wikipedia:Furosemide
- oboInOwl#hasAlternativeId
- CHEBI:5198
- oboInOwl#id
- CHEBI:47426
- generic_name
- Furosemide Micro
- brand_name
- Lasix
- brand_name_base
- Lasix
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_35703
- BFO_0000053
- http://purl.obolibrary.org/obo/DRON_00020327
- has_treatment
- http://purl.obolibrary.org/obo/DOID_12555
- package_marketing_start_date
- 20221217
- rxcui
- 2621028
- unii
- 7LXU5N7ZO5
- spl_set_id
- 13ba97a7-598a-76a4-e063-6294a90a45c5
- manufacturer_name
- Northwind Pharmaceuticals, LLC
- core#notation
- CHEBI:47426
- pharm_class_epc
- Loop Diuretic [EPC]
- pharm_class
- Increased Diuresis at Loop of Henle [PE]
- pharm_class_pe
- Increased Diuresis at Loop of Henle [PE]
- upc
- 0368071453416
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- active_ingredient_strength
- 40 mg/4mL
- active_ingredient_name
- FUROSEMIDE
- nui
- N0000175590
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect25295
- owl#annotatedSource
- t228414
- owl#someValuesFrom
- t3933055