ecothiopate
CHEBI:CHEBI_4753
Definition
The phosphorothioate obtained by formal condensation of diethyl phosphate with N,N,N-trimethyl-2-sulfanylethanaminium. An irreversible acetylcholinesterase inhibitor, its iodide salt is used an ocular antihypertensive in the treatment of open-angle glaucoma, particularly when other drugs have proved inadequate.
Chemical Information
- Molecular Formula
- C9H23NO3PS
- Molecular Mass
- 256.32300
- Charge
- +1
- SMILES
- CCOP(=O)(OCC)SCC[N+](C)(C)C
- InChI
- InChI=1S/C9H23NO3PS/c1-6-12-14(11,13-7-2)15-9-8-10(3,4)5/h6-9H2,1-5H3/q+1
- InChIKey
- BJOLKYGKSZKIGU-UHFFFAOYSA-N
Alternative Names
- (2-diethoxyphosphinylthioethyl)trimethylammonium
- 2-[(diethoxyphosphoryl)sulfanyl]-N,N,N-trimethylethanaminium
- Echothiophate
- ecothiopate
- ecothiopatum
Drug Classification
-
organic thiophosphateView Class →
CHEBI:37512
-
phosphocholinesView Class →
CHEBI:36700
-
t227106
-
t227656
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 89778
- oboInOwl#hasDbXref
- Wikipedia:Echothiophate
- core#notation
- CHEBI:4753
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 89778
- oboInOwl#hasDbXref
- Wikipedia:Echothiophate
- oboInOwl#id
- CHEBI:4753
- core#notation
- CHEBI:4753
- rxcui
- 205739
- dosage_form
- POWDER
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- listing_expiration_date
- 20251231
- route
- OPHTHALMIC
- marketing_start_date
- 19600627
- package_marketing_start_date
- 27-JUN-60
- active_ingredient_strength
- 1 kg/kg
- labeler_name
- Fera Pharmaceuticals, LLC
- generic_name
- Echothiophate Iodide
- brand_name
- Phospholine Iodide
- brand_name_base
- Phospholine Iodide
- product_ndc
- 65392-1402
- application_number
- NDA011963
- manufacturer_name
- Fera Pharmaceuticals, LLC
- spl_id
- 15d45f49-e1a5-4547-e063-6394a90a7ecf
- package_ndc
- 65392-1402-0
- package_description
- .5 kg in 1 BOTTLE, GLASS (65392-1402-0)
- spl_set_id
- 8afc8951-db76-4f27-8752-7c0d6aa47244
- upc
- 0348102053051
- active_ingredient_name
- ECHOTHIOPHATE IODIDE
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_37733
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- owl#annotatedSource
- t228274
- owl#someValuesFrom
- t3512690