Discuss This Drug

Roflumilast

CHEBI:CHEBI_47657

Definition

A benzamide obtained by formal condensation of the carboxy group of 3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzoic acid with the amino group of 3,5-dichloropyridin-4-amine. Used for treatment of bronchial asthma and chronic obstructive pulmonary disease.

Chemical Information

Molecular Formula
C17H14Cl2F2N2O3
Molecular Mass
403.20700
Charge
0
SMILES
FC(F)Oc1ccc(cc1OCC1CC1)C(=O)Nc1c(Cl)cncc1Cl
InChI
InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13(26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7,9,17H,1-2,8H2,(H,22,23,24)
InChIKey
MNDBXUUTURYVHR-UHFFFAOYSA-N

Alternative Names

  • 3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
  • Daliresp
  • roflumilast
  • roflumilastum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1091836
oboInOwl#hasDbXref
Wikipedia:Roflumilast
core#notation
CHEBI:47657

Additional References

Wikipedia:Roflumilast

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1091836
oboInOwl#hasDbXref
Wikipedia:Roflumilast
oboInOwl#id
CHEBI:47657
core#notation
CHEBI:47657
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_68844
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
owl#annotatedSource
t228366
owl#someValuesFrom
t3892835