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Clomipramine

CHEBI:CHEBI_47780

Definition

A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.

Chemical Information

Molecular Formula
C19H23ClN2
Molecular Mass
314.85210
Charge
0
SMILES
CN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc12
InChI
InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3
InChIKey
GDLIGKIOYRNHDA-UHFFFAOYSA-N

Alternative Names

  • 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine
  • 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine
  • 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE
  • 3-chloroimipramine
  • chlorimipramine
  • Clomipramine
  • G 34586
  • monochlorimipramine

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Clomipramine
DRON_00010000
2597
core#notation
CHEBI:47780

Additional References

Wikipedia:Clomipramine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
CAPSULE
marketing_start_date
19891229
labeler_name
Lundbeck Pharmaceuticals Italy S.p.A.
application_number
ANDA216440
product_ndc
69238-1110
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Clomipramine
DRON_00010000
2597
oboInOwl#hasAlternativeId
CHEBI:47359
oboInOwl#id
CHEBI:47780
generic_name
Clomipramine hydrochloride
brand_name
ANAFRANIL
brand_name_base
ANAFRANIL
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_77402
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_47499
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723855
package_ndc
70710-1066-9
listing_expiration_date
20241231
route
ORAL
spl_id
06fe88a1-5edb-653f-e063-6394a90a5cdc
core#notation
CHEBI:47780
package_marketing_start_date
01-APR-08
manufacturer_name
Lifestar Pharma LLC
package_description
100 CAPSULE in 1 BOTTLE (46708-409-31)
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_64209
rxcui
857305
active_ingredient_strength
25 kg/25kg
pharm_class
Tricyclic Antidepressant [EPC]
active_ingredient_name
CLOMIPRAMINE HYDROCHLORIDE
unii
2LXW0L6GWJ
spl_set_id
be907f61-d918-45f1-89d7-ab61086c83a7
upc
0370710106614
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_8986
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect25333
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_64209
owl#annotatedSource
t228435
owl#someValuesFrom
t2884670