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emedastine

CHEBI:CHEBI_4779

Definition

1-Methyl-1,4-diazepane in which the hydrogen attached to the nitrogen at position 4 is substituted by a 1-(2-ethoxyethyl)-1H-benzimidazol-2-yl group. A relatively selective histamine H1 antagonist, it is used as the difumatate salt for allergic rhinitis, urticaria, and pruritic skin disorders, and in eyedrops for the symptomatic relief of allergic conjuntivitis.

Chemical Information

Molecular Formula
C17H26N4O
Molecular Mass
302.41450
Charge
0
SMILES
CCOCCn1c(nc2ccccc12)N1CCCN(C)CC1
InChI
InChI=1S/C17H26N4O/c1-3-22-14-13-21-16-8-5-4-7-15(16)18-17(21)20-10-6-9-19(2)11-12-20/h4-5,7-8H,3,6,9-14H2,1-2H3
InChIKey
KBUZBQVCBVDWKX-UHFFFAOYSA-N

Alternative Names

  • 1-(2-Ethoxy-ethyl)-2-(4-methyl-[1,4]diazepan-1-yl)-1H-benzoimidazole
  • 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole
  • 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzimidazole
  • 1-[2-(ethoxy)ethyl]-2-(4-methyl-1-homopiperazinyl)benzimidazole
  • emedastina
  • emedastine
  • Emedastine
  • EMEDASTINE
  • emedastinum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
28144
oboInOwl#hasDbXref
Wikipedia:Emedastine
core#notation
CHEBI:4779

Additional References

Wikipedia:Emedastine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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chebi_ontology
DRON_00010000
28144
oboInOwl#hasDbXref
Wikipedia:Emedastine
oboInOwl#hasAlternativeId
CHEBI:119712
oboInOwl#id
CHEBI:4779
core#notation
CHEBI:4779
listing_expiration_date
20241231
dosage_form
POWDER
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
active_ingredient_strength
1 kg/kg
generic_name
EMEDASTINE DIFUMARATE
active_ingredient_name
EMEDASTINE DIFUMARATE
product_ndc
12863-100
labeler_name
Shiratori Pharmaceutical Co., Ltd.
marketing_start_date
19980215
spl_id
c1a1a77a-0a9e-499f-bf27-5d0e6ef3be19
package_ndc
12863-100-01
package_description
1 BAG in 1 DRUM (12863-100-01) / 3 kg in 1 BAG
package_marketing_start_date
15-FEB-98
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37955
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https://w3id.org/def/predibionto#has_side_effect25385
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