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Enalapril

CHEBI:CHEBI_4784

Definition

A dicarboxylic acid monoester that is ethyl 4-phenylbutanoate in which a hydrogen alpha to the carboxy group is substituted by the amino group of L-alanyl-L-proline (S-configuration).

Chemical Information

Molecular Formula
C20H28N2O5
Molecular Mass
376.44670
Charge
0
SMILES
CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
InChI
InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
InChIKey
GBXSMTUPTTWBMN-XIRDDKMYSA-N

Alternative Names

  • (S)-1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline
  • (S)-1-{(S)-2-[1-((S)-Ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid
  • 1-(N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester
  • analapril
  • enalapril
  • Enalapril
  • ENALAPRIL
  • enalaprila
  • enalaprilum
  • N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3827
oboInOwl#hasDbXref
Wikipedia:Enalapril
core#notation
CHEBI:4784

Additional References

Wikipedia:Enalapril

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

route
ORAL
package_ndc
71335-9604-5
spl_id
2680a3cb-c330-9425-e063-6394a90a9271
package_description
120 TABLET in 1 BOTTLE (71335-9604-5)
product_ndc
60429-183
listing_expiration_date
20241231
marketing_start_date
20210125
package_marketing_start_date
25-SEP-09
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
SOLUTION
labeler_name
Preferred Pharmaceuicals Inc.
application_number
ANDA212408
rxcui
1435630
manufacturer_name
Preferred Pharmaceuicals Inc.
unii
9O25354EPJ
spl_set_id
2e4ecc3a-ec6d-418b-99a8-95ad3e1c59d6
has_treatment
http://purl.obolibrary.org/obo/DOID_0080016
owl#someValuesFrom
t1018422
active_ingredient_name
ENALAPRIL MALEATE
active_ingredient_strength
1 kg/kg
nui
M0471776
upc
0369452237465
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3827
oboInOwl#hasDbXref
Wikipedia:Enalapril
oboInOwl#hasAlternativeId
CHEBI:116847
oboInOwl#id
CHEBI:4784
generic_name
Enalapril Maleate Oral Solution
brand_name
Enalapril Maleate Oral Solution
brand_name_base
Enalapril Maleate Oral Solution
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_4786
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50266
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723853
core#notation
CHEBI:4784
pharm_class_epc
Thiazide Diuretic [EPC]
pharm_class
Decreased Blood Pressure [PE]
pharm_class_pe
Increased Diuresis [PE]
pharm_class_cs
Thiazides [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect25634
owl#annotatedSource
t228437