Discuss This Drug

vinorelbine

CHEBI:CHEBI_480999

Definition

A vinca alkaloid with a norvinblastine skeleton.

Chemical Information

Molecular Formula
C45H54N4O8
Molecular Mass
778.93230
Charge
0
SMILES
CCC1=C[C@@H]2CN(C1)Cc1c([nH]c3ccccc13)[C@@](C2)(C(=O)OC)c1cc2c(cc1OC)N(C)[C@@H]1[C@]22CCN3CC=C[C@](CC)([C@@H]23)[C@@H](OC(C)=O)[C@]1(O)C(=O)OC
InChI
InChI=1S/C45H54N4O8/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7/h10-15,19-21,28,37-39,46,53H,8-9,16-18,22-25H2,1-7H3/t28-,37-,38+,39+,42+,43+,44-,45-/m0/s1
InChIKey
GBABOYUKABKIAF-IELIFDKJSA-N

Alternative Names

  • Nor-5'-anhydrovinblastine
  • vinorelbina
  • vinorelbine
  • vinorelbinum
  • methyl (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-acetoxy-15-[(6R,8S)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
39541
oboInOwl#hasDbXref
Patent:US4307100
core#notation
CHEBI:480999

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
39541
oboInOwl#hasDbXref
Patent:US4307100
oboInOwl#id
CHEBI:480999
core#notation
CHEBI:480999
rxcui
1729422
product_type
BULK INGREDIENT
listing_expiration_date
20241231
marketing_category
BULK INGREDIENT
dosage_form
INJECTION, SOLUTION
labeler_name
Sagent Pharmaceuticals
manufacturer_name
Sagent Pharmaceuticals
active_ingredient_strength
1 g/g
route
INTRAVENOUS
marketing_start_date
20100602
package_marketing_start_date
28-DEC-17
generic_name
Vinorelbine Tartrate
brand_name
Vinorelbine
brand_name_base
Vinorelbine
product_ndc
25021-204
application_number
ANDA091106
spl_id
dfa03517-f452-450c-8eb6-d946c0350248
active_ingredient_name
VINORELBINE TARTRATE
package_ndc
25021-204-05
package_description
1 VIAL in 1 CARTON (25021-204-05) / 5 mL in 1 VIAL
unii
253GQW851Q
spl_set_id
10a70995-e04d-4044-b1dc-c9aa27460397
upc
0345963607553
pharm_class
Vinca Alkaloids [CS]
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_47868
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_6202
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_112674
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect25700
owl#annotatedSource
t228290
owl#someValuesFrom
t2997533