Discuss This Drug

Ketoconazole

CHEBI:CHEBI_48339

Definition

A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.

Chemical Information

Molecular Formula
C26H28Cl2N4O4
Molecular Mass
531.43048
Charge
0
SMILES
CC(=O)N1CCN(CC1)c1ccc(OCC2COC(Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1
InChI
InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3
InChIKey
XMAYWYJOQHXEEK-UHFFFAOYSA-N

Alternative Names

  • 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
6135
oboInOwl#hasDbXref
LINCS:LSM-5148
core#notation
CHEBI:48339

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

route
TOPICAL
package_ndc
58159-091-05
spl_id
17306f85-843b-443b-bed9-7a185195b671
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
6135
oboInOwl#hasDbXref
LINCS:LSM-5148
oboInOwl#id
CHEBI:48339
generic_name
KETOCONAZOLE Shampoo
brand_name
POAGCI Ketoconazole VCP-KAD001
brand_name_base
POAGCI Ketoconazole VCP-KAD001
product_ndc
58159-091
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00698710
dosage_form
SHAMPOO, SUSPENSION
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
labeler_name
Cureworth Drugs & Intermediates Pvt Ltd
marketing_start_date
19960524
application_number
ANDA210457
package_marketing_start_date
24-MAY-96
package_description
1 kg in 1 CONTAINER (51927-3194-0)
listing_expiration_date
20241231
rxcui
608844
manufacturer_name
THIRTY MADISON INC
unii
R9400W927I
spl_set_id
2435001f-82a8-a781-e063-6394a90a9628
core#notation
CHEBI:48339
pharm_class_epc
Azole Antifungal [EPC]
pharm_class
Cytochrome P450 3A5 Inhibitors [MoA]
pharm_class_cs
Azoles [CS]
pharm_class_moa
Cytochrome P450 3A5 Inhibitors [MoA]
nui
N0000190115
active_ingredient_strength
10.2 mg/mL
active_ingredient_name
KETOCONAZOLE
upc
6926112134225
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0070547
owl#annotatedSource
t227985
owl#someValuesFrom
t3970055