Discuss This Drug

esmolol

CHEBI:CHEBI_4856

Definition

A racemate comprising equimolar amounts of (R)- and (S)-esmolol. A cardioselective and short-acting beta1 receptor blocker with rapid onset but lacking intrinsic sympathomimetic and membrane-stabilising properties, it is used as the hydrochloride salt in the management of supraventricular arrhythmias, and for the control of hypertension and tachycardia during surgery. While the S enantiomer possesses all of the heart rate control, both enantiomers contribute to lowering blood pressure.

Chemical Information

Molecular Formula
C16H25NO4
Molecular Mass
295.375
Charge
0

Alternative Names

  • (+-)-esmolol
  • (+-)-methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate
  • 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl ester
  • esmolol
  • Esmolol
  • ESMOLOL
  • esmololum
  • Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate
  • methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate
  • rac-methyl 3-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}propanoate

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:4856
DRON_00010000
49737
oboInOwl#hasDbXref
Wikipedia:Esmolol

Additional References

Wikipedia:Esmolol

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
marketing_start_date
20191208
route
INTRAVENOUS
labeler_name
Huzhou Zhanwang Pharmaceutical Co., Ltd.
application_number
ANDA205520
spl_id
6011c3bd-db0a-48c2-9baa-c6160554df01
package_ndc
10019-668-10
package_description
10 BAG in 1 CARTON (10019-668-10) / 100 mL in 1 BAG
marketing_category
ANDA
rxcui
1736547
package_marketing_start_date
20191208
active_ingredient_strength
100 mg/10mL
manufacturer_name
Henry Schein, Inc.
active_ingredient_name
ESMOLOL HYDROCHLORIDE
unii
V05260LC8D
spl_set_id
220a07b8-5c68-41a3-8705-fd91f14c50b4
upc
0355150421015
core#notation
CHEBI:4856
pharm_class
beta-Adrenergic Blocker [EPC]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect26066
owl#annotatedSource
t231788
owl#someValuesFrom
t2988545
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
49737
oboInOwl#hasDbXref
Wikipedia:Esmolol
oboInOwl#hasAlternativeId
CHEBI:143354
oboInOwl#id
CHEBI:4856
product_type
BULK INGREDIENT
dosage_form
INJECTION, SOLUTION
generic_name
esmolol hydrochloride in sodium chloride
brand_name
Brevibloc
brand_name_base
Brevibloc
product_ndc
10019-668
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35530
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_143310
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00020323
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_60075