Discuss This Drug

Estramustine

CHEBI:CHEBI_4868

Definition

A carbamate ester obtained by the formal condensation of the hydroxy group of 17beta-estradiol with the carboxy group of bis(2-chloroethyl)carbamic acid.

Chemical Information

Molecular Formula
C23H31Cl2NO3
Molecular Mass
440.40300
Charge
0
SMILES
[H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc1cc(OC(=O)N(CCCl)CCCl)ccc21
InChI
InChI=1S/C23H31Cl2NO3/c1-23-9-8-18-17-5-3-16(29-22(28)26(12-10-24)13-11-25)14-15(17)2-4-19(18)20(23)6-7-21(23)27/h3,5,14,18-21,27H,2,4,6-13H2,1H3/t18-,19-,20+,21+,23+/m1/s1
InChIKey
FRPJXPJMRWBBIH-RBRWEJTLSA-N

Alternative Names

  • (17beta)-17-hydroxyestra-1(10),2,4-trien-3-yl bis(2-chloroethyl)carbamate
  • 17beta-Estradiol 3-(bis(2-chloroethyl)carbamate)
  • Estradiol 3-(N,N-bis(2-chloroethyl)carbamate)
  • estramustina
  • estramustine
  • Estramustine
  • estramustinum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
4089
oboInOwl#hasDbXref
Wikipedia:Estramustine
core#notation
CHEBI:4868

Additional References

Wikipedia:Estramustine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

has_treatment
http://purl.obolibrary.org/obo/DOID_10283
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect26087
owl#annotatedSource
t231728
owl#someValuesFrom
t876303
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
4089
oboInOwl#hasDbXref
Wikipedia:Estramustine
oboInOwl#id
CHEBI:4868
core#notation
CHEBI:4868
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_22333
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_16469
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class