Discuss This Drug

Ethacrynate

CHEBI:CHEBI_4876

Definition

An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Chemical Information

Molecular Formula
C13H12Cl2O4
Molecular Mass
303.13800
Charge
0
SMILES
CCC(=C)C(=O)c1ccc(OCC(O)=O)c(Cl)c1Cl
InChI
InChI=1S/C13H12Cl2O4/c1-3-7(2)13(18)8-4-5-9(12(15)11(8)14)19-6-10(16)17/h4-5H,2-3,6H2,1H3,(H,16,17)
InChIKey
AVOLMBLBETYQHX-UHFFFAOYSA-N

Alternative Names

  • (2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)acetic acid
  • [2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid
  • acide etacrynique
  • acido etacrinico
  • acidum etacrynicum
  • Crinuryl
  • Edecril
  • Edecrina
  • Endecril
  • Etacrinic acid
  • etacrynic acid
  • Ethacrynate
  • ethacrynic acid
  • Hidromedin
  • Hydromedin
  • Methylenebutyrylphenoxyacetic acid
  • Mingit
  • Otacril
  • Reomax
  • Taladren
  • Uregit

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
62349
oboInOwl#hasDbXref
Wikipedia:Etacrynic_acid
core#notation
CHEBI:4876

Additional References

Wikipedia:Etacrynic_acid

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
62349
oboInOwl#hasDbXref
Wikipedia:Etacrynic_acid
oboInOwl#id
CHEBI:4876
core#notation
CHEBI:4876
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50184
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_15366
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00020327
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
owl#annotatedSource
t231767
owl#someValuesFrom
t2991294