Ethosuximide

CHEBI:CHEBI_4887

Definition

A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.

Chemical Information

Molecular Formula
C7H11NO2
Molecular Mass
141.16770
Charge
0
SMILES
CCC1(C)CC(=O)NC1=O
InChI
InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)
InChIKey
HAPOVYFOVVWLRS-UHFFFAOYSA-N

Alternative Names

  • (+-)-2-ethyl-2-methylsuccinimide
  • 2-ethyl-2-methylsuccinimide
  • 2-methyl-2-ethylsuccinimide
  • 3-ethyl-3-methyl-2,5-pyrrolidinedione
  • 3-ethyl-3-methylpyrrolidine-2,5-dione
  • 3-ethyl-3-methylsuccinimide
  • 3-methyl-3-ethylpyrrolidine-2,5-dione
  • 3-methyl-3-ethylsuccinimide
  • Aethosuximide
  • alpha-ethyl-alpha-methylsuccinimide
  • alpha-methyl-alpha-ethylsuccinimide
  • ethosuximide
  • Ethosuximide
  • ethosuximidum
  • etosuximida
  • gamma-ethyl-gamma-methyl-succinimide
  • gamma-methyl-gamma-ethyl-succinimide

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:4887
oboInOwl#hasDbXref
Wikipedia:Ethosuximide
DRON_00010000
4135

Additional References

Wikipedia:Ethosuximide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:4887
rxcui
755357
nui
N0000008486
pharm_class_epc
Anti-epileptic Agent [EPC]
pharm_class
Decreased Central Nervous System Disorganized Electrical Activity [PE]
pharm_class_pe
Decreased Central Nervous System Disorganized Electrical Activity [PE]
active_ingredient_strength
50 kg/50kg
manufacturer_name
Strides Pharma Science Limited
package_marketing_start_date
20231023
active_ingredient_name
ETHOSUXIMIDE
unii
5SEH9X1D1D
spl_set_id
19c924c2-f558-4c78-9277-2d7e0df2f505
upc
0364380878063
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
listing_expiration_date
20241231
route
ORAL
marketing_start_date
19960227
labeler_name
B.V. Katwijk Chemie
marketing_category
NDA AUTHORIZED GENERIC
application_number
ANDA211928
spl_id
2646752a-b2e8-4167-bf80-6ed8fa869917
package_ndc
59762-2350-7
package_description
1 BOTTLE, PLASTIC in 1 CARTON (59762-2350-7) / 474 mL in 1 BOTTLE, PLASTIC
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Ethosuximide
DRON_00010000
4135
oboInOwl#hasAlternativeId
CHEBI:131811
oboInOwl#id
CHEBI:4887
generic_name
ETHOSUXIMIDE
brand_name
ETHOSUXIMIDE
brand_name_base
ETHOSUXIMIDE
product_type
BULK INGREDIENT
dosage_form
CAPSULE, LIQUID FILLED
product_ndc
59762-2350
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_194338
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00020328
has_treatment
http://purl.obolibrary.org/obo/DOID_1823
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_110381
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect26263
owl#annotatedSource
t231833
owl#someValuesFrom
t874982