Ethosuximide
CHEBI:CHEBI_4887
Definition
A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.
Chemical Information
- Molecular Formula
- C7H11NO2
- Molecular Mass
- 141.16770
- Charge
- 0
- SMILES
- CCC1(C)CC(=O)NC1=O
- InChI
- InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)
- InChIKey
- HAPOVYFOVVWLRS-UHFFFAOYSA-N
Alternative Names
- (+-)-2-ethyl-2-methylsuccinimide
- 2-ethyl-2-methylsuccinimide
- 2-methyl-2-ethylsuccinimide
- 3-ethyl-3-methyl-2,5-pyrrolidinedione
- 3-ethyl-3-methylpyrrolidine-2,5-dione
- 3-ethyl-3-methylsuccinimide
- 3-methyl-3-ethylpyrrolidine-2,5-dione
- 3-methyl-3-ethylsuccinimide
- Aethosuximide
- alpha-ethyl-alpha-methylsuccinimide
- alpha-methyl-alpha-ethylsuccinimide
- ethosuximide
- Ethosuximide
- ethosuximidum
- etosuximida
- gamma-ethyl-gamma-methyl-succinimide
- gamma-methyl-gamma-ethyl-succinimide
Treatment Applications
-
hot water epilepsyView Disease →
DOID:0081104
-
congenital myopathy 14View Disease →
DOID:0081346
-
juvenile myoclonic epilepsy 10View Disease →
DOID:0111325
-
juvenile myoclonic epilepsy 3View Disease →
DOID:0111326
-
juvenile myoclonic epilepsy 4View Disease →
DOID:0111327
-
juvenile myoclonic epilepsy 9View Disease →
DOID:0111328
-
MERRF syndromeView Disease →
DOID:310
-
Lafora diseaseView Disease →
DOID:3534
Drug Classification
-
pyrrolidinoneView Class →
CHEBI:38275
-
dicarboximideView Class →
CHEBI:35356
-
t230558
-
t230989
-
t231559
-
t231714
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:4887
- oboInOwl#hasDbXref
- Wikipedia:Ethosuximide
- DRON_00010000
- 4135
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- core#notation
- CHEBI:4887
- rxcui
- 755357
- nui
- N0000008486
- pharm_class_epc
- Anti-epileptic Agent [EPC]
- pharm_class
- Decreased Central Nervous System Disorganized Electrical Activity [PE]
- pharm_class_pe
- Decreased Central Nervous System Disorganized Electrical Activity [PE]
- active_ingredient_strength
- 50 kg/50kg
- manufacturer_name
- Strides Pharma Science Limited
- package_marketing_start_date
- 20231023
- active_ingredient_name
- ETHOSUXIMIDE
- unii
- 5SEH9X1D1D
- spl_set_id
- 19c924c2-f558-4c78-9277-2d7e0df2f505
- upc
- 0364380878063
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- listing_expiration_date
- 20241231
- route
- ORAL
- marketing_start_date
- 19960227
- labeler_name
- B.V. Katwijk Chemie
- marketing_category
- NDA AUTHORIZED GENERIC
- application_number
- ANDA211928
- spl_id
- 2646752a-b2e8-4167-bf80-6ed8fa869917
- package_ndc
- 59762-2350-7
- package_description
- 1 BOTTLE, PLASTIC in 1 CARTON (59762-2350-7) / 474 mL in 1 BOTTLE, PLASTIC
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Ethosuximide
- DRON_00010000
- 4135
- oboInOwl#hasAlternativeId
- CHEBI:131811
- oboInOwl#id
- CHEBI:4887
- generic_name
- ETHOSUXIMIDE
- brand_name
- ETHOSUXIMIDE
- brand_name_base
- ETHOSUXIMIDE
- product_type
- BULK INGREDIENT
- dosage_form
- CAPSULE, LIQUID FILLED
- product_ndc
- 59762-2350
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_194338
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- BFO_0000053
- http://purl.obolibrary.org/obo/DRON_00020328
- has_treatment
- http://purl.obolibrary.org/obo/DOID_1823
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_110381
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect26263
- owl#annotatedSource
- t231833
- owl#someValuesFrom
- t874982