ezetimibe
CHEBI:CHEBI_49040
Definition
A beta-lactam that is azetidin-2-one which is substituted at 1, 3, and 4 by p-fluorophenyl, 3-(p-fluorophenyl)-3-hydroxypropyl, and 4-hydroxyphenyl groups, respectively (the 3R,3'S,4S enantiomer).
Chemical Information
- Molecular Formula
- C24H21F2NO3
- Molecular Mass
- 409.42520
- Charge
- 0
- SMILES
- [H][C@]1(CC[C@H](O)c2ccc(F)cc2)C(=O)N(c2ccc(F)cc2)[C@]1([H])c1ccc(O)cc1
- InChI
- InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1
- InChIKey
- OLNTVTPDXPETLC-XPWALMASSA-N
Alternative Names
- (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
- Ezedoc
- ezetimiba
- ezetimibe
- ezetimibum
- Ezetrol
- Zetia
Drug Classification
-
organofluorine compoundView Class →
CHEBI:37143
-
beta-lactamView Class →
CHEBI:35627
-
azetidinesView Class →
CHEBI:38777
-
t230690
-
t231042
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 341248
- oboInOwl#hasDbXref
- Wikipedia:Ezetimibe
- core#notation
- CHEBI:49040
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- dosage_form
- POWDER
- labeler_name
- Orient Pharma Co., Ltd.
- application_number
- NDA021445
- product_ndc
- 14501-0008
- route
- ORAL
- package_ndc
- 60312-0314-0
- spl_id
- 0b35820e-49ae-e3fa-e063-6294a90a42f9
- listing_expiration_date
- 20241231
- marketing_start_date
- 20170702
- package_description
- 1 BAG in 1 DRUM (60312-0314-0) / 37500 TABLET in 1 BAG
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 341248
- oboInOwl#hasDbXref
- Wikipedia:Ezetimibe
- oboInOwl#id
- CHEBI:49040
- generic_name
- Ezetimibe and Simvastatin
- brand_name
- Ezetimibe and Simvastatin
- brand_name_base
- Ezetimibe and Simvastatin
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_35821
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- package_marketing_start_date
- 20170702
- rxcui
- 1245449
- manufacturer_name
- Orient Pharma Co., Ltd.
- unii
- EOR26LQQ24
- spl_set_id
- 174e45e0-45bb-48b7-9e60-8f6cfc1d22bb
- core#notation
- CHEBI:49040
- active_ingredient_strength
- 2 kg/2kg
- active_ingredient_name
- EZETIMIBE
- nui
- N0000175911
- pharm_class_epc
- Dietary Cholesterol Absorption Inhibitor [EPC]
- pharm_class
- Decreased Cholesterol Absorption [PE]
- pharm_class_moa
- Hydroxymethylglutaryl-CoA Reductase Inhibitors [MoA]
- pharm_class_pe
- Decreased Cholesterol Absorption [PE]
- upc
- 0378206178015
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_14117
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect26319
- owl#annotatedSource
- t231848
- owl#someValuesFrom
- t3776548