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Etodolac

CHEBI:CHEBI_4909

Definition

A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active.

Chemical Information

Molecular Formula
C17H21NO3
Molecular Mass
287.35350
Charge
0
SMILES
CCc1cccc2c3CCOC(CC)(CC(O)=O)c3[nH]c12
InChI
InChI=1S/C17H21NO3/c1-3-11-6-5-7-12-13-8-9-21-17(4-2,10-14(19)20)16(13)18-15(11)12/h5-7,18H,3-4,8-10H2,1-2H3,(H,19,20)
InChIKey
NNYBQONXHNTVIJ-UHFFFAOYSA-N

Alternative Names

  • (+-)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
  • (1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid
  • (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid
  • 1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid
  • 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
  • 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid
  • etodolac
  • ETODOLAC
  • etodolaco
  • etodolacum
  • ETODOLIC ACID

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Etodolac
DRON_00010000
24605
core#notation
CHEBI:4909

Additional References

Wikipedia:Etodolac

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

package_ndc
71335-0126-8
listing_expiration_date
20241231
spl_id
f54b22a8-f424-83b3-e053-2a95a90ad65e
marketing_start_date
19980311
package_description
25 kg in 1 DRUM (17373-0186-0)
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Etodolac
DRON_00010000
24605
oboInOwl#hasAlternativeId
CHEBI:126431
oboInOwl#id
CHEBI:4909
generic_name
Etodolac Micronized
brand_name
Etodolac ER
brand_name_base
ETODOLAC
product_ndc
17373-0186
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50629
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
labeler_name
KREATIVE ACTIVES PRIVATE LIMITED
dosage_form
TABLET, COATED
application_number
ANDA075078
manufacturer_name
Doc Rx
package_marketing_start_date
20180407
route
ORAL
core#notation
CHEBI:4909
pharm_class
Non-Steroidal [CS]
pharm_class_epc
Nonsteroidal Anti-inflammatory Drug [EPC]
pharm_class_moa
Cyclooxygenase Inhibitors [MoA]
pharm_class_cs
Anti-Inflammatory Agents, Non-Steroidal [CS]
brand_name_suffix
ER
upc
0351672405144
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
active_ingredient_name
ETODOLAC
rxcui
359500
nui
N0000175722
active_ingredient_strength
15 kg/15kg
unii
2M36281008
spl_set_id
20b2c2c3-02ab-6377-e063-6294a90a7b23
has_treatment
http://purl.obolibrary.org/obo/DOID_0080321
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect26374
owl#annotatedSource
t231832
owl#someValuesFrom
t1082740