CETP inhibitor
CHEBI:CHEBI_49205
Definition
Any inhibitor of cholesterylester transfer protein (CETP), which transfers cholesterol from high density lipoproteins (HDL, the 'good' cholesterol-containing particles) to low or very low density lipoproteins (LDL or VLDL, the 'bad' cholesterol-containing particles). Inhibition of this process results in higher HDL levels and lower LDL levels. CETP inhibitors are under investigation as potential drugs to reduce the risk of arteriosclerotic vascular disease (atherosclerosis).
Alternative Names
- CETP inhibitors
- cholesteryl ester transfer protein inhibitor
Treatment Applications
-
primary hypoalphalipoproteinemia 1View Disease →
DOID:0080957
-
primary hypoalphalipoproteinemia 2View Disease →
DOID:0080958
-
Huntington's disease-like 2View Disease →
DOID:0090104
-
autosomal recessive hypercholesterolemiaView Disease →
DOID:0090105
-
hyperalphalipoproteinemia 1View Disease →
DOID:0111369
-
apolipoprotein C-III deficiencyView Disease →
DOID:0111370
-
familial apolipoprotein A5 deficiencyView Disease →
DOID:0111421
-
familial hypercholesterolemiaView Disease →
DOID:13810
-
hypobetalipoproteinemiaView Disease →
DOID:1390
-
abetalipoproteinemiaView Disease →
DOID:1386
-
Tangier diseaseView Disease →
DOID:1388
-
cholesterol embolismView Disease →
DOID:1461
Drug Classification
-
inhibitorView Class →
CHEBI:35222
-
biochemical roleView Class →
CHEBI:52206
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:49205
- oboInOwl#hasDbXref
- Wikipedia:CETP_inhibitor
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#id
- CHEBI:49205
- core#notation
- CHEBI:49205
- oboInOwl#hasDbXref
- Wikipedia:CETP_inhibitor
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_0040096
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_109006
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_38545
- owl#someValuesFrom
- t210131
- owl#annotatedSource
- t231594