Discuss This Drug

lapatinib

CHEBI:CHEBI_49603

Chemical Information

Molecular Formula
C29H26ClFN4O4S
Molecular Mass
581.05840
Charge
0
SMILES
CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1
InChI
InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)
InChIKey
BCFGMOOMADDAQU-UHFFFAOYSA-N

Alternative Names

  • GW 572016
  • N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine
  • N-[3-chloro-4-(3-fluorobenzyloxy)phenyl]-6-[5-({[2-(methanesulfonyl)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine
  • N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE
  • Tykerb

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
480167
oboInOwl#hasDbXref
Wikipedia:Lapatinib
core#notation
CHEBI:49603

Additional References

Wikipedia:Lapatinib

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
480167
oboInOwl#hasDbXref
Wikipedia:Lapatinib
oboInOwl#hasAlternativeId
CHEBI:49602
oboInOwl#id
CHEBI:49603
generic_name
Lapatinib Ditosylate Monohydrate
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
POWDER
marketing_start_date
20140911
labeler_name
BDR Lifesciences Private Limited
product_ndc
33656-0014
spl_id
de2173fc-887a-fa3d-e053-2a95a90adb73
package_ndc
33656-0014-1
package_description
1 kg in 1 DRUM (33656-0014-1)
brand_name
TYKERB
brand_name_base
TYKERB
application_number
NDA022059
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38637
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_5115
core#notation
CHEBI:49603
rxcui
672152
active_ingredient_strength
1 kg/kg
pharm_class
Protein Kinase Inhibitors [MoA]
manufacturer_name
Novartis Pharmaceuticals Corporation
package_marketing_start_date
14-APR-20
active_ingredient_name
LAPATINIB
unii
G873GX646R
spl_set_id
eee37f88-ec6a-4c30-b8aa-e2c71f93088c
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0060088
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect26592
owl#annotatedSource
t234832
owl#someValuesFrom
t978880