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Pizotyline

CHEBI:CHEBI_50212

Definition

A benzocycloheptathiophene that is 9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene 4-ylidene)-1-methylpiperidine which is joined from the 4 position to the 4 position of an N-methylpiperidine moiety by a double bond. It is a sedating antihistamine, with strong serotonin antagonist and weak antimuscarinic activity. It is generally used as the malate salt for the treatment of migraine and the prevention of headache attacks during cluster periods.

Chemical Information

Molecular Formula
C19H21NS
Molecular Mass
295.44278
Charge
0
SMILES
CN1CCC(CC1)=C1c2ccccc2CCc2sccc12
InChI
InChI=1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3
InChIKey
FIADGNVRKBPQEU-UHFFFAOYSA-N

Alternative Names

  • 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine
  • pizotifen
  • pizotifene
  • pizotifeno
  • pizotifenum
  • Pizotyline

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
8373
oboInOwl#hasDbXref
Wikipedia:Pizotifen
core#notation
CHEBI:50212

Additional References

Wikipedia:Pizotifen

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
8373
oboInOwl#hasDbXref
Wikipedia:Pizotifen
oboInOwl#id
CHEBI:50212
core#notation
CHEBI:50212
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_48279
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_18049
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_50318
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_50318
owl#annotatedSource
t235266
owl#someValuesFrom
t772803