Discuss This Drug

Esomeprazole

CHEBI:CHEBI_50275

Definition

A 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole that has S configuration at the sulfur atom. An inhibitor of gastric acid secretion, it is used (generally as its sodium or magnesium salt) for the treatment of gastro-oesophageal reflux disease, dyspepsia, peptic ulcer disease, and Zollinger-Ellison syndrome.

Chemical Information

Molecular Formula
C17H19N3O3S
Molecular Mass
345.41600
Charge
0
SMILES
COc1ccc2[nH]c(nc2c1)[S@@](=O)Cc1ncc(C)c(OC)c1C
InChI
InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)/t24-/m0/s1
InChIKey
SUBDBMMJDZJVOS-DEOSSOPVSA-N

Alternative Names

  • (-)-omeprazole
  • (S)-(-)-omeprazole
  • (S)-omeprazole
  • 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
  • Alenia
  • Escz
  • Esofag
  • esomeprazol
  • esomeprazole
  • esomeprazolum
  • Inexium paranova

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:50275
DRON_00010000
283742
oboInOwl#hasDbXref
Wikipedia:Esomeprazole

Additional References

Wikipedia:Esomeprazole

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
labeler_name
medsourcer pharmaceuticals
dosage_form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
application_number
ANDA212507
product_ndc
11014-0383
package_description
500 CAPSULE, COATED PELLETS in 1 BOTTLE (67877-571-05)
marketing_start_date
20231020
rxcui
1743279
unii
C5N25H3803
spl_set_id
85a963c1-9c13-4eb7-826b-08d5a991fe28
manufacturer_name
Lake Erie Medical DBA Quality Care Products LLC
package_marketing_start_date
20200215
listing_expiration_date
20241231
spl_id
a73e0237-491f-4c60-8204-28ea8006d0b7
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_112642
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect26875
package_ndc
70377-055-13
core#notation
CHEBI:50275
pharm_class_moa
Proton Pump Inhibitors [MoA]
pharm_class
Proton Pump Inhibitors [MoA]
pharm_class_epc
Proton Pump Inhibitor [EPC]
brand_name_suffix
I.V.
upc
0041220534777
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
brand_name_base
berkley and jensen heartburn treatment
brand_name
members mark esomeprazole magnesium
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
283742
oboInOwl#hasDbXref
Wikipedia:Esomeprazole
oboInOwl#id
CHEBI:50275
generic_name
Esomeprazole mgdi micro
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_49200
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_enantiomer_of
http://purl.obolibrary.org/obo/CHEBI_77262
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_77264
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00020324
has_treatment
http://purl.obolibrary.org/obo/DOID_9206
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_77264
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_7772
owl#annotatedSource
t235334
owl#someValuesFrom
t3068674
route
INTRAVENOUS
active_ingredient_strength
8 kg/8kg
nui
N0000000147
active_ingredient_name
ESOMEPRAZOLE STRONTIUM