Discuss This Drug

Esomeprazole

CHEBI:CHEBI_50275

Definition

A 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole that has S configuration at the sulfur atom. An inhibitor of gastric acid secretion, it is used (generally as its sodium or magnesium salt) for the treatment of gastro-oesophageal reflux disease, dyspepsia, peptic ulcer disease, and Zollinger-Ellison syndrome.

Chemical Information

Molecular Formula
C17H19N3O3S
Molecular Mass
345.41600
Charge
0
SMILES
COc1ccc2[nH]c(nc2c1)[S@@](=O)Cc1ncc(C)c(OC)c1C
InChI
InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)/t24-/m0/s1
InChIKey
SUBDBMMJDZJVOS-DEOSSOPVSA-N

Alternative Names

  • (-)-omeprazole
  • (S)-(-)-omeprazole
  • (S)-omeprazole
  • 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
  • Alenia
  • Escz
  • Esofag
  • esomeprazol
  • esomeprazole
  • esomeprazolum
  • Inexium paranova

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
283742
oboInOwl#hasDbXref
Wikipedia:Esomeprazole
core#notation
CHEBI:50275

Additional References

Wikipedia:Esomeprazole

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

marketing_start_date
20231020
labeler_name
Dr.Reddy's Laboratories Limited
route
INTRAVENOUS
package_ndc
49927-0006-0
spl_id
1a222320-7601-4402-82d4-b6f5cb0c4d04
dosage_form
GRANULE, FOR SUSPENSION, EXTENDED RELEASE
product_ndc
33342-306
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_112642
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect26875
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
283742
oboInOwl#hasDbXref
Wikipedia:Esomeprazole
oboInOwl#id
CHEBI:50275
generic_name
Esomeprazole mgdi micro
brand_name
berkley and jensen heartburn treatment
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_49200
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_enantiomer_of
http://purl.obolibrary.org/obo/CHEBI_77262
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_77264
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00020324
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
application_number
ANDA212507
listing_expiration_date
20241231
package_description
90 CAPSULE, COATED PELLETS in 1 BOTTLE (71205-706-90)
brand_name_base
berkley and jensen heartburn treatment
package_marketing_start_date
21-JAN-13
core#notation
CHEBI:50275
pharm_class_moa
Proton Pump Inhibitors [MoA]
pharm_class
Proton Pump Inhibitors [MoA]
pharm_class_epc
Proton Pump Inhibitor [EPC]
brand_name_suffix
I.V.
upc
0041220534777
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
manufacturer_name
medsourcer pharmaceuticals
active_ingredient_strength
8 kg/8kg
nui
N0000000147
active_ingredient_name
ESOMEPRAZOLE STRONTIUM
spl_set_id
59502415-e290-45b8-b96c-ea7c2a601ab4
rxcui
1743279
unii
C5N25H3803
has_treatment
http://purl.obolibrary.org/obo/DOID_9206
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_77264
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_7772
owl#annotatedSource
t235334
owl#someValuesFrom
t3068674