Discuss This Drug

Milrinone

CHEBI:CHEBI_50693

Definition

A member of the class of bipyridines that is 2-pyridone which is substituted at positions 3, 5, and 6 by cyano, pyrid-4-yl, and methyl groups, respectively. It is used (particularly intravenously, as the lactate) for the short-term management of severe heart failure.

Chemical Information

Molecular Formula
C12H9N3O
Molecular Mass
211.21948
Charge
0
SMILES
Cc1[nH]c(=O)c(cc1-c1ccncc1)C#N
InChI
InChI=1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16)
InChIKey
PZRHRDRVRGEVNW-UHFFFAOYSA-N

Alternative Names

  • 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile
  • 2-methyl-6-oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrile
  • milrinona
  • milrinone
  • Milrinone
  • milrinonum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:50693
DRON_00010000
52769
oboInOwl#hasDbXref
Wikipedia:Milrinone

Additional References

Wikipedia:Milrinone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:50693
pharm_class
Phosphodiesterase 3 Inhibitors [MoA]
upc
0372485502011
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rxcui
1791861
manufacturer_name
Somerset Therapeutics, LLC
package_marketing_start_date
30-JUL-07
active_ingredient_strength
200 ug/mL
spl_set_id
bb0157d0-a414-43fa-81e0-8c92d717f1b2
active_ingredient_name
MILRINONE
unii
9K8XR81MO8
package_description
10 VIAL in 1 CARTON (0143-9326-10) / 20 mL in 1 VIAL (0143-9326-01)
listing_expiration_date
20241231
labeler_name
Huzhou Zhanwang Pharmaceutical Co., Ltd.
marketing_start_date
20070730
route
INTRAVENOUS
spl_id
753b9d9d-f4a7-4604-8bfe-20d0a811883a
package_ndc
0409-2045-10
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
52769
oboInOwl#hasDbXref
Wikipedia:Milrinone
oboInOwl#hasAlternativeId
CHEBI:6938
oboInOwl#id
CHEBI:50693
generic_name
Milrinone Lactate in 5% Dextrose
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
INJECTION, SOLUTION
brand_name
Milrinone Lactate in Dextrose
brand_name_base
Milrinone Lactate in Dextrose
product_ndc
0409-2045
application_number
ANDA211671
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50568
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_107174
has_treatment
http://purl.obolibrary.org/obo/DOID_3827
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect27051
owl#annotatedSource
t238760
owl#someValuesFrom
t3001007