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Mitoxantrone

CHEBI:CHEBI_50729

Definition

A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.

Chemical Information

Molecular Formula
C22H28N4O6
Molecular Mass
444.48108
Charge
0
SMILES
OCCNCCNc1ccc(NCCNCCO)c2C(=O)c3c(O)ccc(O)c3C(=O)c12
InChI
InChI=1S/C22H28N4O6/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32/h1-4,23-30H,5-12H2
InChIKey
KKZJGLLVHKMTCM-UHFFFAOYSA-N

Alternative Names

  • 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE
  • 1,4-dihydroxy-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione
  • mitoxantrona
  • mitoxantrone
  • Mitoxantrone
  • mitoxantronum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
7005
oboInOwl#hasDbXref
Wikipedia:Mitoxantrone
core#notation
CHEBI:50729

Additional References

Wikipedia:Mitoxantrone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
7005
oboInOwl#hasDbXref
Wikipedia:Mitoxantrone
oboInOwl#hasAlternativeId
CHEBI:6955
oboInOwl#id
CHEBI:50729
core#notation
CHEBI:50729
generic_name
MITOXANTRONE HYDROCHLORIDE
brand_name
Mitoxantrone
brand_name_base
Mitoxantrone
rxcui
197989
product_type
BULK INGREDIENT
listing_expiration_date
20251231
marketing_category
BULK INGREDIENT
dosage_form
INJECTION, SOLUTION, CONCENTRATE
route
INTRAVENOUS
active_ingredient_strength
1 g/g
pharm_class
Topoisomerase Inhibitors [MoA]
labeler_name
Chongqing Carelife Pharmaceutical Co., Ltd.
manufacturer_name
Hospira, Inc.
marketing_start_date
20060411
active_ingredient_name
MITOXANTRONE HYDROCHLORIDE
product_ndc
58598-0005
application_number
ANDA076871
package_marketing_start_date
13-JUL-17
spl_id
27781ed3-5a68-74b0-e063-6394a90a6e02
package_ndc
58598-0005-1
package_description
1 BAG in 1 CAN (58598-0005-1) / 1000 g in 1 BAG
unii
U6USW86RD0
spl_set_id
accf9569-4b57-4e83-a7db-4e890a75d1ba
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35480
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_4550
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect27083
owl#annotatedSource
t238519
owl#someValuesFrom
t522174