Discuss This Drug

calcipotriol

CHEBI:CHEBI_50749

Definition

A seco-cholestane that is 26,27-cyclo-9,10-secocholesta-5,7,10,22-tetraene carrying additional hydroxy substituents at positions 1, 3 and 24. It is used (as its hydrate) in combination with betamethasone dipropionate, a corticosteroid, for the topical treatment of plaque psoriasis in adult patients.

Chemical Information

Molecular Formula
C27H40O3
Molecular Mass
412.606
Charge
0
SMILES
[C@@H]1(C[C@@H](C/C(/C1=C)=C/C=C\2/[C@]3([C@](CCC2)([C@](CC3)([C@@H](/C=C/[C@@H](O)C4CC4)C)[H])C)[H])O)O
InChI
InChI=1S/C27H40O3/c1-17(6-13-25(29)20-8-9-20)23-11-12-24-19(5-4-14-27(23,24)3)7-10-21-15-22(28)16-26(30)18(21)2/h6-7,10,13,17,20,22-26,28-30H,2,4-5,8-9,11-12,14-16H2,1,3H3/b13-6+,19-7+,21-10-/t17-,22-,23-,24+,25-,26+,27-/m1/s1
InChIKey
LWQQLNNNIPYSNX-UROSTWAQSA-N

Alternative Names

  • (1S,3R,5Z,7E,22E,24S)-26,27-cyclo-9,10-secocholesta-5,7,10,22-tetraene-1,3,24-triol
  • Calcipotriene
  • calcipotriol
  • Calcipotriol
  • CALCIPOTRIOL
  • Daivonex
  • Dovonex

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:50749
DRON_00010000
29365
oboInOwl#hasDbXref
Reaxys:5309193

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

route
TOPICAL
package_ndc
0713-0848-92
package_description
2 BOTTLE in 1 CARTON (0713-0848-92) / 60 g in 1 BOTTLE
spl_id
b80b014e-5787-7763-e053-2a95a90a3289
core#notation
CHEBI:50749
pharm_class
Vitamin D Analog [EPC]
active_ingredient_strength
64 mg/g
nui
N0000175849
pharm_class_cs
Vitamin D [CS]
active_ingredient_name
CALCIPOTRIENE HYDRATE
spl_set_id
1eba330b-ce18-6b12-e063-6294a90a8763
upc
0316714763019
pharm_class_epc
Vitamin D Analog [EPC]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
dosage_form
AEROSOL, FOAM
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
listing_expiration_date
20241231
marketing_start_date
20080912
labeler_name
MC2 Therapeutics Ltd
application_number
ANDA210765
product_ndc
48943-0022
rxcui
2471878
package_marketing_start_date
01-AUG-03
manufacturer_name
MC2 Therapeutics Ltd
unii
143NQ3779B
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
29365
generic_name
Calcipotriene and Betamethasone dipropionate
brand_name
Wynzora
brand_name_base
Wynzora
oboInOwl#hasDbXref
Reaxys:5309193
oboInOwl#hasAlternativeId
CHEBI:43947
oboInOwl#id
CHEBI:50749
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50748
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
has_treatment
http://purl.obolibrary.org/obo/DOID_0080932
owl#annotatedSource
t238783
owl#someValuesFrom
t2997716