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EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor

CHEBI:CHEBI_50750

Definition

A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.

Alternative Names

  • DNA gyrase inhibitor
  • DNA gyrase inhibitors
  • DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitor
  • DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitors
  • DNA topoisomerase (ATP-hydrolysing) inhibitor
  • DNA topoisomerase (ATP-hydrolysing) inhibitors
  • DNA topoisomerase II inhibitor
  • DNA topoisomerase II inhibitors
  • EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitor
  • EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitors
  • EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitors
  • EC 5.99.1.3 inhibitor
  • EC 5.99.1.3 inhibitors
  • inhibitor of type II topoisomerase
  • inhibitors of type II topoisomerase
  • topoisomerase II inhibitor
  • topoisomerase II inhibitors
  • topoisomerase-II inhibitor
  • topoisomerase-II inhibitors
  • type II DNA topoisomerase inhibitor
  • type II DNA topoisomerase inhibitors

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:50750

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Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasAlternativeId
CHEBI:50234
oboInOwl#id
CHEBI:50750
core#notation
CHEBI:50750
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_77795
owl#someValuesFrom
t310379
owl#annotatedSource
t238765