Doxycycline
CHEBI:CHEBI_50845
Definition
Tetracycline in which the 5beta-hydrogen is replaced by a hydroxy group, while the 6alpha-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis.
Chemical Information
- Molecular Formula
- C22H24N2O8
- Molecular Mass
- 444.43464
- Charge
- 0
- SMILES
- [H][C@@]12[C@@H](C)c3cccc(O)c3C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])[C@H]2O
- InChI
- InChI=1S/C22H24N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31)/t7-,10+,14+,15-,17-,22-/m0/s1
- InChIKey
- JBIWCJUYHHGXTC-AKNGSSGZSA-N
Alternative Names
- (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
- (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE
- 5-hydroxy-alpha-6-deoxytetracycline
- 6alpha-deoxy-5-oxytetracycline
- doxiciclina
- Doxycyclin
- doxycycline
- Doxycycline
- doxycycline (anhydrous)
- doxycyclinum
- Jenacyclin
- Supracyclin
- Vibramycin
Treatment Applications
Drug Classification
-
tetracyclinesView Class →
CHEBI:26895
-
t237550
-
t237955
-
t238117
-
t238479
-
t238688
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Doxycycline
- DRON_00010000
- 3640
- core#notation
- CHEBI:50845
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Doxycycline
- DRON_00010000
- 3640
- oboInOwl#hasAlternativeId
- CHEBI:4713
- oboInOwl#id
- CHEBI:50845
- generic_name
- DOXYCYCLINE MONOHYDRATE
- brand_name
- LymePak
- brand_name_base
- LymePak
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_67079
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- labeler_name
- Yancheng Suhai Pharmaceutical Co., Ltd.
- application_number
- ANDA065134
- product_ndc
- 0143-3141
- marketing_start_date
- 19830202
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- dosage_form
- FOR SUSPENSION
- route
- INTRAVENOUS
- spl_id
- 48982ef0-96da-4cf1-9c3b-57eea42ac082
- listing_expiration_date
- 20241231
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_110134
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect27276
- owl#annotatedSource
- t238790
- owl#someValuesFrom
- t2996501
- package_ndc
- 68788-8464-3
- package_description
- 50 CAPSULE, GELATIN COATED in 1 BOTTLE, PLASTIC (0143-3142-50)
- Antibiotic_Name
- http://purl.obolibrary.org/obo/DOID_0040083
- Medication
- http://purl.obolibrary.org/obo/DOID_0050011
- has_treatment
- http://purl.obolibrary.org/obo/DOID_0080929
- package_marketing_start_date
- 01-SEP-04
- rxcui
- 2099769
- manufacturer_name
- Aqua Pharmaceuticals
- spl_set_id
- 2c7795c9-9e4e-477a-ad9f-01e4c55c06b6
- active_ingredient_strength
- 100 mg/10mL
- active_ingredient_name
- DOXYCYCLINE ANHYDROUS
- nui
- M0021223
- upc
- 0372789308500
- unii
- 334895S862
- core#notation
- CHEBI:50845
- pharm_class
- Tetracycline-class Drug [EPC]
- pharm_class_cs
- Tetracyclines [Chemical/Ingredient]
- pharm_class_epc
- Tetracycline-class Drug [EPC]
- brand_name_suffix
- CAP
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class