Flucytosine
CHEBI:CHEBI_5100
Definition
An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Chemical Information
- Molecular Formula
- C4H4FN3O
- Molecular Mass
- 129.09250
- Charge
- 0
- SMILES
- Nc1nc(=O)[nH]cc1F
- InChI
- InChI=1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)
- InChIKey
- XRECTZIEBJDKEO-UHFFFAOYSA-N
Alternative Names
- 4-amino-5-fluoropyrimidin-2(1H)-one
- 5-FC
- 5-Fluorocystosine
- 5-Fluorocytosine
- Ancobon (TN)
- Ancotil
- flucytosina
- flucytosine
- flucytosinum
Drug Classification
-
pyrimidine antifungal drugView Class →
CHEBI:87205
-
nucleoside analogueView Class →
CHEBI:60783
-
organofluorine compoundView Class →
CHEBI:37143
-
aminopyrimidineView Class →
CHEBI:38338
-
pyrimidoneView Class →
CHEBI:38337
-
t241076
-
t241760
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:5100
- oboInOwl#hasDbXref
- Wikipedia:Flucytosine
- DRON_00010000
- 4451
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- listing_expiration_date
- 20241231
- route
- ORAL
- package_marketing_start_date
- 19711126
- marketing_start_date
- 19711126
- spl_id
- 1cbd0275-70bd-f7b7-e063-6394a90a1af9
- package_ndc
- 42973-193-00
- package_description
- 50 kg in 1 DRUM (42973-193-00)
- core#notation
- CHEBI:5100
- rxcui
- 207127
- nui
- N0000175467
- pharm_class
- Nucleoside Analog Antifungal [EPC]
- active_ingredient_strength
- 1 kg/kg
- manufacturer_name
- AvPAK
- active_ingredient_name
- FLUCYTOSINE
- unii
- D83282DT06
- spl_set_id
- 97937a4e-f29d-4e83-aedf-70f46f105355
- upc
- 0301873555100
- pharm_class_epc
- Nucleoside Analog Antifungal [EPC]
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Flucytosine
- DRON_00010000
- 4451
- oboInOwl#id
- CHEBI:5100
- generic_name
- FLUCYTOSINE
- brand_name
- ANCOBON
- brand_name_base
- ANCOBON
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- dosage_form
- CAPSULE
- labeler_name
- AvPAK
- product_ndc
- 42973-193
- application_number
- ANDA201566
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_16040
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_50266
- has_treatment
- http://purl.obolibrary.org/obo/DOID_2058
- owl#annotatedSource
- t242271
- owl#someValuesFrom
- t714215