Flucytosine

CHEBI:CHEBI_5100

Definition

An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.

Chemical Information

Molecular Formula
C4H4FN3O
Molecular Mass
129.09250
Charge
0
SMILES
Nc1nc(=O)[nH]cc1F
InChI
InChI=1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)
InChIKey
XRECTZIEBJDKEO-UHFFFAOYSA-N

Alternative Names

  • 4-amino-5-fluoropyrimidin-2(1H)-one
  • 5-FC
  • 5-Fluorocystosine
  • 5-Fluorocytosine
  • Ancobon (TN)
  • Ancotil
  • flucytosina
  • flucytosine
  • flucytosinum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:5100
oboInOwl#hasDbXref
Wikipedia:Flucytosine
DRON_00010000
4451

Additional References

Wikipedia:Flucytosine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
ORAL
package_marketing_start_date
19711126
marketing_start_date
19711126
spl_id
1cbd0275-70bd-f7b7-e063-6394a90a1af9
package_ndc
42973-193-00
package_description
50 kg in 1 DRUM (42973-193-00)
core#notation
CHEBI:5100
rxcui
207127
nui
N0000175467
pharm_class
Nucleoside Analog Antifungal [EPC]
active_ingredient_strength
1 kg/kg
manufacturer_name
AvPAK
active_ingredient_name
FLUCYTOSINE
unii
D83282DT06
spl_set_id
97937a4e-f29d-4e83-aedf-70f46f105355
upc
0301873555100
pharm_class_epc
Nucleoside Analog Antifungal [EPC]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Flucytosine
DRON_00010000
4451
oboInOwl#id
CHEBI:5100
generic_name
FLUCYTOSINE
brand_name
ANCOBON
brand_name_base
ANCOBON
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
CAPSULE
labeler_name
AvPAK
product_ndc
42973-193
application_number
ANDA201566
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_16040
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50266
has_treatment
http://purl.obolibrary.org/obo/DOID_2058
owl#annotatedSource
t242271
owl#someValuesFrom
t714215