Flumazenil
CHEBI:CHEBI_5103
Definition
An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Chemical Information
- Molecular Formula
- C15H14FN3O3
- Molecular Mass
- 303.289
- Charge
- 0
- SMILES
- C1=NC(=C2N1C=3C(C(N(C2)C)=O)=CC(=CC3)F)C(OCC)=O
- InChI
- InChI=1S/C15H14FN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3
- InChIKey
- OFBIFZUFASYYRE-UHFFFAOYSA-N
Alternative Names
- Anexate
- ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
- flumazenil
- flumazenilo
- flumazenilum
- Lanexat
Drug Classification
-
t241770
-
ethyl esterView Class →
CHEBI:23990
-
organofluorine compoundView Class →
CHEBI:37143
-
imidazobenzodiazepineView Class →
CHEBI:142118
-
t241415
-
t241578
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:5103
- DRON_00010000
- 4457
- oboInOwl#hasDbXref
- Wikipedia:Flumazenil
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- core#notation
- CHEBI:5103
- rxcui
- 204508
- manufacturer_name
- Henry Schein, Inc
- package_marketing_start_date
- 19-JAN-01
- route
- INTRAVENOUS
- active_ingredient_strength
- 1 kg/kg
- active_ingredient_name
- FLUMAZENIL
- package_ndc
- 71872-7038-1
- package_description
- 1 VIAL, MULTI-DOSE in 1 BAG (71872-7038-1) / 5 mL in 1 VIAL, MULTI-DOSE
- unii
- 40P7XK9392
- spl_set_id
- 6673efde-057a-a889-e053-2a91aa0a517b
- nui
- N0000175680
- upc
- 0371872703819
- pharm_class_epc
- Benzodiazepine Antagonist [EPC]
- pharm_class
- Benzodiazepine Antagonist [EPC]
- spl_id
- 61456aa8-ed8f-4c3c-be90-9bf4b2d46025
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 4457
- oboInOwl#hasDbXref
- Wikipedia:Flumazenil
- oboInOwl#id
- CHEBI:5103
- generic_name
- FLUMAZENIL
- brand_name
- FLUMAZENIL
- brand_name_base
- FLUMAZENIL
- product_type
- BULK INGREDIENT
- listing_expiration_date
- 20241231
- marketing_category
- BULK INGREDIENT
- dosage_form
- INJECTION, SOLUTION
- labeler_name
- Henry Schein, Inc
- marketing_start_date
- 20010119
- product_ndc
- 71872-7038
- application_number
- ANDA076955
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- BFO_0000053
- http://purl.obolibrary.org/obo/DRON_00000072
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_90757
- has_treatment
- http://purl.obolibrary.org/obo/DOID_12380
- owl#annotatedSource
- t242210
- owl#someValuesFrom
- t512086