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bosentan

CHEBI:CHEBI_51450

Chemical Information

Molecular Formula
C27H29N5O6S
Molecular Mass
551.61526
Charge
0
SMILES
COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1
InChI
InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)
InChIKey
GJPICJJJRGTNOD-UHFFFAOYSA-N

Alternative Names

  • 4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide
  • 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide
  • bosentan
  • bosentanum
  • p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:51450
oboInOwl#hasDbXref
Wikipedia:Bosentan
DRON_00010000
75207

Additional References

Wikipedia:Bosentan

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
ORAL
marketing_start_date
20231214
spl_id
a294af23-4dde-4ba0-b6f9-8b64388f69bf
package_ndc
65015-770-61
package_description
100 kg in 1 DRUM (65015-770-61)
rxcui
1989085
package_marketing_start_date
23-MAR-10
manufacturer_name
Zydus Pharmaceuticals USA Inc.
pharm_class_moa
Endothelin Receptor Antagonists [MoA]
pharm_class
Endothelin Receptor Antagonists [MoA]
active_ingredient_strength
62.5 mg/1
nui
N0000175364
active_ingredient_name
BOSENTAN ANHYDROUS
unii
XUL93R30K2
spl_set_id
39b2a85f-4322-42d4-b420-1b1d52569143
pharm_class_epc
Endothelin Receptor Antagonist [EPC]
upc
0305912511607
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
core#notation
CHEBI:51450
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Bosentan
DRON_00010000
75207
generic_name
BOSENTAN MONOHYDRATE
brand_name
Tracleer
brand_name_base
Tracleer
oboInOwl#id
CHEBI:51450
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
TABLET, FOR SUSPENSION
labeler_name
Zydus Pharmaceuticals USA Inc.
product_ndc
65015-770
application_number
NDA021290
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_51451
has_treatment
http://purl.obolibrary.org/obo/DOID_12918
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect27967
owl#annotatedSource
t242035
owl#someValuesFrom
t3214290