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nilotinib

CHEBI:CHEBI_52172

Chemical Information

Molecular Formula
C28H22F3N7O
Molecular Mass
529.51580
Charge
0
SMILES
Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F
InChI
InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37)
InChIKey
HHZIURLSWUIHRB-UHFFFAOYSA-N

Alternative Names

  • 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
  • AMN 107
  • AMN107
  • nilotinib
  • nilotinib
  • nilotinibum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:52172
DRON_00010000
662281
oboInOwl#hasDbXref
Wikipedia:Nilotinib

Additional References

Wikipedia:Nilotinib

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

rxcui
2002719
listing_expiration_date
20241231
route
ORAL
package_marketing_start_date
08-JUL-22
manufacturer_name
Azurity Pharmaceuticals, Inc.
active_ingredient_name
NILOTINIB HYDROCHLORIDE DIHYDRATE
spl_id
08ffad54-6e85-7c26-e063-6394a90ab472
package_ndc
81955-0017-1
package_description
10 kg in 1 DRUM (81955-0017-1)
marketing_start_date
20151231
unii
F41401512X
spl_set_id
6093952a-5248-45cb-ad17-33716a411146
core#notation
CHEBI:52172
active_ingredient_strength
350 kg/350kg
pharm_class_moa
UGT1A1 Inhibitors [MoA]
pharm_class
UGT1A1 Inhibitors [MoA]
nui
N0000191272
pharm_class_epc
Kinase Inhibitor [EPC]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
662281
oboInOwl#hasDbXref
Wikipedia:Nilotinib
oboInOwl#id
CHEBI:52172
generic_name
NILOTINIB HYDROCHLORIDE
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
CAPSULE
labeler_name
VALARY LAB PRIVATE LIMITED
product_ndc
81955-0017
brand_name
Tasigna
brand_name_base
Tasigna
application_number
NDA022068
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38637
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
has_treatment
http://purl.obolibrary.org/obo/DOID_6367
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect28183
owl#annotatedSource
t245736
owl#someValuesFrom
t1054933