Discuss This Drug

gatifloxacin

CHEBI:CHEBI_5280

Definition

A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.

Chemical Information

Molecular Formula
C19H22FN3O4
Molecular Mass
375.39410
Charge
0
SMILES
COc1c(N2CCNC(C)C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1
InChI
InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26)
InChIKey
XUBOMFCQGDBHNK-UHFFFAOYSA-N

Alternative Names

  • 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
  • 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid
  • 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • AM 1155
  • gatifloxacin
  • gatifloxacine
  • gatifloxacino
  • gatifloxacinum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Gatifloxacin
DRON_00010000
228476
core#notation
CHEBI:5280

Additional References

Wikipedia:Gatifloxacin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Gatifloxacin
DRON_00010000
228476
oboInOwl#hasAlternativeId
CHEBI:101712
oboInOwl#id
CHEBI:5280
generic_name
Gatifloxacin Sesquihydrate
brand_name
Gatifloxacin
brand_name_base
Gatifloxacin
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
SOLUTION/ DROPS
labeler_name
Kyorin Pharmaceutical Group Facility Co., Ltd.
product_ndc
58159-102
application_number
ANDA204227
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50750
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:5280
rxcui
992395
listing_expiration_date
20241231
pharm_class
Quinolones [CS]
active_ingredient_strength
1000 g/1000g
marketing_start_date
20190730
route
OPHTHALMIC
manufacturer_name
Sandoz Inc
package_marketing_start_date
08-SEP-11
active_ingredient_name
GATIFLOXACIN ANHYDROUS
spl_id
ea2e96d0-db80-4e5b-8cc2-684614512837
package_ndc
58159-102-05
package_description
5 kg in 1 DRUM (58159-102-05)
unii
L4618BD7KJ
spl_set_id
9e6fcd14-1fee-493f-811c-e18cbfbee65b
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_11184
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect28453
owl#annotatedSource
t245745
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t844207