Glipizide

CHEBI:CHEBI_5384

Definition

An N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus.

Chemical Information

Molecular Formula
C21H27N5O4S
Molecular Mass
445.53500
Charge
0
SMILES
Cc1cnc(cn1)C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1
InChI
InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28)
InChIKey
ZJJXGWJIGJFDTL-UHFFFAOYSA-N

Alternative Names

  • 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea
  • Aldiab
  • CP 28,720
  • CP 28720
  • CP-28,720
  • Digrin
  • Dipazide
  • Glibenese
  • Glibetin
  • Glican
  • Glidiab
  • Glipid
  • glipizida
  • glipizide
  • glipizidum
  • Gluco-Rite
  • Glucolip
  • Glucotrol
  • Glucozide
  • Glupitel
  • Glupizide
  • Glyde
  • Glydiazinamide
  • K 4024
  • Melizide
  • Mindiab
  • Minidab
  • Minidiab
  • Minodiab
  • N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methylpyrazine-2-carboxamide
  • N-{4-[beta-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylurea
  • Napizide
  • Ozidia
  • Sucrazide

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Glipizide
DRON_00010000
4821
core#notation
CHEBI:5384

Additional References

Wikipedia:Glipizide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Glipizide
DRON_00010000
4821
oboInOwl#id
CHEBI:5384
generic_name
Glipizide and metformin hcl
brand_name
Glucotrol XL
brand_name_base
GLIPIZIDE ER
product_ndc
0904-6637
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_77194
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
package_ndc
0904-6637-61
marketing_start_date
20090805
labeler_name
Northwind Pharmaceuticals, LLC
package_description
100 BLISTER PACK in 1 CARTON (0904-6637-61) / 1 TABLET in 1 BLISTER PACK
route
ORAL
spl_id
7a8f022b-3f21-9409-e053-2a91aa0a34c8
rxcui
865573
unii
X7WDT95N5C
spl_set_id
d3b5677c-2265-47c8-beeb-bf12106056ba
manufacturer_name
Coupler LLC
product_type
BULK INGREDIENT
marketing_category
EXPORT ONLY
dosage_form
TABLET, FILM COATED, EXTENDED RELEASE
application_number
ANDA074305
package_marketing_start_date
20181015
listing_expiration_date
20241231
core#notation
CHEBI:5384
brand_name_suffix
ER
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_11711
owl#annotatedSource
t245765
owl#someValuesFrom
t3006189
active_ingredient_strength
1 kg/kg
active_ingredient_name
GLIPIZIDE
pharm_class
Sulfonylurea Compounds [CS]
nui
M0020795
pharm_class_epc
Sulfonylurea [EPC]
pharm_class_cs
Sulfonylurea Compounds [CS]
upc
0371205041908