Discuss This Drug

Glyburide

CHEBI:CHEBI_5441

Definition

An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Chemical Information

Molecular Formula
C23H28ClN3O5S
Molecular Mass
494.00400
Charge
0
SMILES
COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1
InChI
InChI=1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29)
InChIKey
ZNNLBTZKUZBEKO-UHFFFAOYSA-N

Alternative Names

  • 1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea
  • 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea
  • 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide
  • 5-chloro-N-(2-{4-[N-(N-cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide
  • Diabeta
  • glibenclamida
  • glibenclamide
  • glibenclamidum
  • Glyburide
  • Glynase
  • Micronase

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Glibenclamide
DRON_00010000
4815
core#notation
CHEBI:5441

Additional References

Wikipedia:Glibenclamide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

package_description
25 kg in 1 DRUM (46438-0064-0)
package_ndc
68382-654-77
product_type
BULK INGREDIENT
dosage_form
POWDER
marketing_category
BULK INGREDIENT
labeler_name
REMEDYREPACK INC.
marketing_start_date
19990511
application_number
ANDA074686
product_ndc
0093-8342
rxcui
861753
manufacturer_name
REMEDYREPACK INC.
unii
SX6K58TVWC
package_marketing_start_date
20240530
spl_set_id
6f65131c-90df-45ab-95fb-c36f411c6fbe
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Glibenclamide
DRON_00010000
4815
oboInOwl#id
CHEBI:5441
generic_name
Glyburide Micronized
brand_name
glyburide and metformin hydrochloride
brand_name_base
glyburide and metformin hydrochloride
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_77194
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
listing_expiration_date
20241231
route
ORAL
spl_id
7a92de57-2525-683e-e053-2a91aa0a7ab7
core#notation
CHEBI:5441
active_ingredient_strength
1.25 mg/1
active_ingredient_name
GLYBURIDE
pharm_class
Sulfonylurea Compounds [CS]
nui
M0020795
pharm_class_epc
Sulfonylurea [EPC]
pharm_class_cs
Sulfonylurea Compounds [CS]
upc
0382804150007
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_1550
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect28707
owl#annotatedSource
t249165
owl#someValuesFrom
t1024886