anidulafungin
CHEBI:CHEBI_55346
Definition
A semisynthetic echinocandin anti-fungal drug. It is active against Aspergillus and Candida species and is used for the treatment of invasive candidiasis.
Chemical Information
- Molecular Formula
- C58H73N7O17
- Molecular Mass
- 1140.23690
- Charge
- 0
- SMILES
- CCCCCOc1ccc(cc1)-c1ccc(cc1)-c1ccc(cc1)C(=O)N[C@H]1C[C@@H](O)[C@@H](O)NC(=O)[C@@H]2[C@@H](O)[C@@H](C)CN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC1=O)[C@@H](C)O)[C@H](O)[C@@H](O)c1ccc(O)cc1)[C@@H](C)O
- InChI
- InChI=1S/C58H73N7O17/c1-5-6-7-24-82-40-22-18-35(19-23-40)33-10-8-32(9-11-33)34-12-14-37(15-13-34)51(74)59-41-26-43(70)54(77)63-56(79)47-48(71)29(2)27-65(47)58(81)45(31(4)67)61-55(78)46(50(73)49(72)36-16-20-38(68)21-17-36)62-53(76)42-25-39(69)28-64(42)57(80)44(30(3)66)60-52(41)75/h8-23,29-31,39,41-50,54,66-73,77H,5-7,24-28H2,1-4H3,(H,59,74)(H,60,75)(H,61,78)(H,62,76)(H,63,79)/t29-,30+,31+,39+,41-,42-,43+,44-,45-,46-,47-,48-,49-,50-,54+/m0/s1
- InChIKey
- JHVAMHSQVVQIOT-MFAJLEFUSA-N
Alternative Names
- anidulafungin
- anidulafungina
- anidulafungine
- anidulafunginum
- Eraxis
- N-{(2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,12,15-tetrahydroxy-6,20-bis[(1R)-1-hydroxyethyl]-16-methyl-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl}-4''-(pentyloxy)-1,1':4',1''-terphenyl-4-carboxamide
Treatment Applications
-
invasive aspergillosisView Disease →
DOID:0050073
-
obsolete tonsillar aspergillosisView Disease →
DOID:0050074
-
pulmonary aspergillomaView Disease →
DOID:0050153
-
aspergillosisView Disease →
DOID:13564
-
candidiasisView Disease →
DOID:1508
-
obsolete candidal pneumoniaView Disease →
DOID:10472
-
obsolete Aspergillus pneumoniaView Disease →
DOID:13165
Drug Classification
-
antibiotic antifungal drugView Class →
CHEBI:87113
-
azamacrocycleView Class →
CHEBI:52898
-
echinocandinView Class →
CHEBI:57248
-
semisynthetic derivativeView Class →
CHEBI:72588
-
heterodetic cyclic peptideView Class →
CHEBI:24533
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 341018
- oboInOwl#hasDbXref
- Wikipedia:Anidulafungin
- core#notation
- CHEBI:55346
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 341018
- oboInOwl#hasDbXref
- Wikipedia:Anidulafungin
- oboInOwl#id
- CHEBI:55346
- core#notation
- CHEBI:55346
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_108361
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect28745
- owl#annotatedSource
- t249088
- owl#someValuesFrom
- t3037644