Discuss This Drug

guanadrel

CHEBI:CHEBI_5555

Definition

A spiroketal resulting from the formal condensation of the keto group of cyclohexanone with the hydroxy groups of 1-(2,3-dihydroxypropyl)guanidine. A postganglionic adrenergic blocking agent formerly used (generally as the sulfate salt) for the management of hypertension, it has been largely superseded by other drugs less likely to cause orthostatic hypotension (dizzy spells on standing up or stretching).

Chemical Information

Molecular Formula
C10H19N3O2
Molecular Mass
213.27680
Charge
0
SMILES
NC(=N)NCC1COC2(CCCCC2)O1
InChI
InChI=1S/C10H19N3O2/c11-9(12)13-6-8-7-14-10(15-8)4-2-1-3-5-10/h8H,1-7H2,(H4,11,12,13)
InChIKey
HPBNRIOWIXYZFK-UHFFFAOYSA-N

Alternative Names

  • 1-(1,4-dioxaspiro[4.5]dec-2-ylmethyl)guanidine
  • guanadrel
  • Guanadrel
  • guanadrelum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
26296
oboInOwl#hasDbXref
Wikipedia:Guanadrel
core#notation
CHEBI:5555

Additional References

Wikipedia:Guanadrel

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
26296
oboInOwl#hasDbXref
Wikipedia:Guanadrel
oboInOwl#id
CHEBI:5555
core#notation
CHEBI:5555
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37887
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_72602
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect28874
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_72602
owl#annotatedSource
t248923
owl#someValuesFrom
t824366