Hydralazine

CHEBI:CHEBI_5775

Definition

The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.

Chemical Information

Molecular Formula
C8H8N4
Molecular Mass
160.17590
Charge
0
SMILES
NNc1nncc2ccccc12
InChI
InChI=1S/C8H8N4/c9-11-8-7-4-2-1-3-6(7)5-10-12-8/h1-5H,9H2,(H,11,12)
InChIKey
RPTUSVTUFVMDQK-UHFFFAOYSA-N

Alternative Names

  • (1Z)-1(2H)-Phthalazinone hydrazone
  • (2H)-Phthalazinone hydrazone
  • 1-hydrazinophthalazine
  • 1-Hydrazinophthalazine
  • 1-Phthalazinylhydrazine
  • 6-Hydralazine
  • hidralazina
  • Hydralazin
  • hydralazine
  • hydralazinum
  • Hydrallazine
  • Hydrazinophthalazine
  • Hydrazone 1(2H)-phthalazinone
  • Hypophthalin
  • Idralazina
  • phthalazin-1-ylhydrazine

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
5470
oboInOwl#hasDbXref
Wikipedia:Hydralazine
core#notation
CHEBI:5775

Additional References

Wikipedia:Hydralazine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
5470
oboInOwl#hasDbXref
Wikipedia:Hydralazine
oboInOwl#id
CHEBI:5775
brand_name
BiDil
brand_name_base
BiDil
generic_name
Hydralazine hydrochloride and Isosorbide dinitrate
product_ndc
70934-764
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35674
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
package_ndc
49452-3544-5
package_marketing_start_date
17-SEP-22
package_description
180 TABLET in 1 BOTTLE (71610-562-80)
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
INJECTION, SOLUTION
labeler_name
Azurity
marketing_start_date
19530115
application_number
ANDA203110
route
INTRAVENOUS
spl_id
2669c5d9-c988-a4e0-e063-6394a90aaccd
manufacturer_name
Azurity
listing_expiration_date
20241231
core#notation
CHEBI:5775
pharm_class_cs
Nitrates [CS]
pharm_class
Nitrates [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
active_ingredient_strength
9.999 kg/9.999kg
nui
N0000009909
pharm_class_epc
Nitrate Vasodilator [EPC]
pharm_class_pe
Vasodilation [PE]
active_ingredient_name
HYDRALAZINE HYDROCHLORIDE
upc
0382804081301
spl_set_id
dca82025-a4cd-4856-aa19-bdf091bf8973
rxcui
905379
unii
FD171B778Y
has_treatment
http://purl.obolibrary.org/obo/DOID_5232
owl#annotatedSource
t249157
owl#someValuesFrom
t3088486