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Hydrochlorothiazide

CHEBI:CHEBI_5778

Definition

A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.

Chemical Information

Molecular Formula
C7H8ClN3O4S2
Molecular Mass
297.73900
Charge
0
SMILES
NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl
InChI
InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13)
InChIKey
JZUFKLXOESDKRF-UHFFFAOYSA-N

Alternative Names

  • 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
  • Esidrix (TN)
  • hidroclorotiazida
  • hydrochlorothiazide
  • hydrochlorothiazidum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
5487
oboInOwl#hasDbXref
Wikipedia:Hydrochlorothiazide
core#notation
CHEBI:5778

Additional References

Wikipedia:Hydrochlorothiazide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
spl_id
24baa7e0-2d0e-5007-e063-6394a90a9b3f
marketing_start_date
20191101
route
ORAL
package_ndc
63187-440-90
product_ndc
68071-3238
product_type
BULK INGREDIENT
dosage_form
CAPSULE, GELATIN COATED
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
labeler_name
Changzhou Pharmaceutical Factory
application_number
ANDA087068
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
5487
oboInOwl#hasDbXref
Wikipedia:Hydrochlorothiazide
oboInOwl#id
CHEBI:5778
generic_name
HYDROCHLOROTHIAZIDE
brand_name
HYDROCHLOROTHIAZIDE
brand_name_base
HYDROCHLOROTHIAZIDE
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35703
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00000059
package_description
30 kg in 1 DRUM (12658-0544-1)
package_marketing_start_date
20171121
active_ingredient_name
HYDROCHLOROTHIAZIDE
active_ingredient_strength
30 kg/30kg
nui
M0471776
upc
0382804031900
spl_set_id
bd5728a2-6322-42e3-bd1e-e4915750e398
manufacturer_name
REMEDYREPACK INC.
has_treatment
http://purl.obolibrary.org/obo/DOID_5232
owl#someValuesFrom
t701139
core#notation
CHEBI:5778
pharm_class_epc
Thiazide Diuretic [EPC]
pharm_class
Thiazides [CS]
pharm_class_pe
Increased Diuresis [PE]
pharm_class_cs
Thiazides [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rxcui
429503
unii
0J48LPH2TH
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_104804
owl#annotatedSource
t249146