Discuss This Drug

Hydroxychloroquine

CHEBI:CHEBI_5801

Definition

An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Chemical Information

Molecular Formula
C18H26ClN3O
Molecular Mass
335.87200
Charge
0
SMILES
CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
InChI
InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)
InChIKey
XXSMGPRMXLTPCZ-UHFFFAOYSA-N

Alternative Names

  • (+-)-hydroxychloroquine
  • 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol
  • 2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol
  • 2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol
  • 7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline
  • 7-chloro-4-(4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino)quinoline
  • 7-chloro-4-[4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino]quinoline
  • 7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline
  • hidroxicloroquina
  • hydroxychloroquine
  • hydroxychloroquinum
  • NSC4375
  • oxichlorochine
  • oxichloroquine
  • Polirreumin

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
5521
oboInOwl#hasDbXref
Wikipedia:Hydroxychloroquine
core#notation
CHEBI:5801

Additional References

Wikipedia:Hydroxychloroquine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

package_ndc
60219-1544-1
package_description
25 kg in 1 DRUM (57451-0198-0)
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
5521
oboInOwl#hasDbXref
Wikipedia:Hydroxychloroquine
oboInOwl#id
CHEBI:5801
generic_name
hydroxychloroquine sulfate
brand_name
Plaquenil
brand_name_base
Plaquenil
product_ndc
57451-0198
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38068
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_3638
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
POWDER
labeler_name
Chongqing Kangle Pharmaceutical Co., Ltd.
marketing_start_date
19980529
application_number
ANDA040766
core#notation
CHEBI:5801
active_ingredient_strength
40 kg/40kg
active_ingredient_name
HYDROXYCHLOROQUINE SULFATE
pharm_class
Antirheumatic Agent [EPC]
upc
0383980001015
spl_set_id
b8f73c62-0fc7-420f-8247-550ffa5c9287
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rxcui
2665284
manufacturer_name
Concordia Pharmaceuticals Inc.
unii
8Q2869CNVH
package_marketing_start_date
27-JUN-13
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_149564
listing_expiration_date
20241231
route
ORAL
spl_id
5906df1c-02a2-4633-8210-0c2b6a31f92c
has_treatment
http://purl.obolibrary.org/obo/DOID_9201
Treatment
http://purl.obolibrary.org/obo/DOID_0040096
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_102843
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_149564
owl#someValuesFrom
t1092411
owl#annotatedSource
t249172