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Ifosfamide

CHEBI:CHEBI_5864

Definition

The simplest member of the class of ifosfamides that is 1,3,2-oxazaphosphinan-2-amine 2-oxide substituted by 2-chloroethyl groups on both the nitrogen atoms respectively. It is a nitrogen mustard alkylating agent used in the treatment of advanced breast cancer.

Chemical Information

Molecular Formula
C7H15Cl2N2O2P
Molecular Mass
261.08600
Charge
0
SMILES
ClCCNP1(=O)OCCCN1CCCl
InChI
InChI=1S/C7H15Cl2N2O2P/c8-2-4-10-14(12)11(6-3-9)5-1-7-13-14/h1-7H2,(H,10,12)
InChIKey
HOMGKSMUEGBAAB-UHFFFAOYSA-N

Alternative Names

  • 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
  • ifosfamida
  • ifosfamide
  • ifosfamidum
  • Iphosphamide
  • Isofosfamide
  • Isophosphamide
  • isosfamide
  • N,3-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:5864
DRON_00010000
5657
oboInOwl#hasDbXref
Wikipedia:Ifosfamide

Additional References

Wikipedia:Ifosfamide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:5864
rxcui
1791595
manufacturer_name
Bamboo US Biidco LCC
active_ingredient_strength
1 kg/kg
pharm_class_moa
Alkylating Activity [MoA]
pharm_class
Alkylating Drug [EPC]
pharm_class_epc
Alkylating Drug [EPC]
nui
N0000175558
package_marketing_start_date
20030128
active_ingredient_name
IFOSFAMIDE
package_description
1 VIAL, SINGLE-DOSE in 1 CARTON (83703-535-02) / 60 mL in 1 VIAL, SINGLE-DOSE (83703-535-16)
unii
UM20QQM95Y
spl_set_id
a311a947-7b78-4226-bfe0-f4aa0be20e27
package_ndc
83703-536-01
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
5657
oboInOwl#hasDbXref
Wikipedia:Ifosfamide
oboInOwl#hasAlternativeId
CHEBI:219640
oboInOwl#id
CHEBI:5864
generic_name
IFOSFAMIDE
brand_name
IFOSFAMIDE
brand_name_base
IFOSFAMIDE
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20251231
dosage_form
INJECTION, POWDER, FOR SOLUTION
labeler_name
Bamboo US Biidco LCC
route
INTRAVENOUS
marketing_start_date
20030128
product_ndc
83703-535
application_number
ANDA076078
spl_id
e9ddd71c-a43f-4ab3-b55b-2e75963da39b
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35703
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
has_treatment
http://purl.obolibrary.org/obo/DOID_0081403
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_111028
owl#annotatedSource
t252614
owl#someValuesFrom
t2997650