Discuss This Drug

cetrorelix

CHEBI:CHEBI_59224

Definition

A synthetic ten-membered oligopeptide comprising N-acetyl-3-(naphthalen-2-yl)-D-alanyl, 4-chloro-D-phenylalanyl, 3-(pyridin-3-yl)-D-alanyl, L-seryl, L-tyrosyl, N(5)-carbamoyl-D-ornithyl, L-leucyl, L-arginyl, L-prolyl, and D-alaninamide residues coupled in sequence. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast.

Chemical Information

Molecular Formula
C70H92ClN17O14
Molecular Mass
1431.03800
Charge
0
SMILES
CC(C)C[C@H](NC(=O)[C@@H](CCCNC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(N)=O
InChI
InChI=1S/C70H92ClN17O14/c1-39(2)31-52(61(94)82-51(15-9-28-77-69(73)74)68(101)88-30-10-16-58(88)67(100)79-40(3)59(72)92)83-60(93)50(14-8-29-78-70(75)102)81-63(96)54(34-43-20-25-49(91)26-21-43)86-66(99)57(38-89)87-65(98)56(36-45-11-7-27-76-37-45)85-64(97)55(33-42-18-23-48(71)24-19-42)84-62(95)53(80-41(4)90)35-44-17-22-46-12-5-6-13-47(46)32-44/h5-7,11-13,17-27,32,37,39-40,50-58,89,91H,8-10,14-16,28-31,33-36,38H2,1-4H3,(H2,72,92)(H,79,100)(H,80,90)(H,81,96)(H,82,94)(H,83,93)(H,84,95)(H,85,97)(H,86,99)(H,87,98)(H4,73,74,77)(H3,75,78,102)/t40-,50-,51+,52+,53-,54+,55-,56-,57+,58+/m1/s1
InChIKey
SBNPWPIBESPSIF-MHWMIDJBSA-N

Alternative Names

  • cetrorelix
  • cetrorelixum
  • N-acetyl-3-(naphthalen-2-yl)-D-alanyl-4-chloro-D-phenylalanyl-3-(pyridin-3-yl)-D-alanyl-L-seryl-L-tyrosyl-N(5)-carbamoyl-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:59224
DRON_00010000
68147
oboInOwl#hasDbXref
Wikipedia:Cetrorelix

Additional References

Wikipedia:Cetrorelix

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:59224
rxcui
284441
active_ingredient_strength
.45 g/.45g
package_marketing_start_date
20000811
active_ingredient_name
CETRORELIX ACETATE
package_description
1 BOTTLE, PLASTIC in 1 BOTTLE, PLASTIC (41701-011-20) / 1.2 g in 1 BOTTLE, PLASTIC (41701-011-19)
manufacturer_name
EMD Serono, Inc.
spl_set_id
aca7768e-28a7-4027-b1d8-e66247665f79
upc
0367184056712
package_ndc
41701-011-22
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect29305
owl#annotatedSource
t252253
owl#someValuesFrom
t3046650
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
68147
oboInOwl#hasDbXref
Wikipedia:Cetrorelix
oboInOwl#id
CHEBI:59224
dosage_form
INJECTION
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
SUBCUTANEOUS
marketing_start_date
20000811
labeler_name
Ambiopharm, Inc.
generic_name
cetrorelix acetate
product_ndc
44087-1225
spl_id
907519f2-732e-4c79-8b64-fa87b1e78175
brand_name
Cetrotide
brand_name_base
Cetrotide
application_number
NDA021197
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_59229
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR