Discuss This Drug

cidofovir dihydrate

CHEBI:CHEBI_59495

Definition

The dihydrate of the anhydrous form of cidofovir. A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.

Chemical Information

Molecular Formula
C8H18N3O8P
Molecular Mass
315.21760
Charge
0
SMILES
O.O.Nc1ccn(C[C@@H](CO)OCP(O)(O)=O)c(=O)n1
InChI
InChI=1S/C8H14N3O6P.2H2O/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16;;/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16);2*1H2/t6-;;/m0../s1
InChIKey
FPKARFMSZDBYQF-ILKKLZGPSA-N

Alternative Names

  • cidofovir
  • (((S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy)methyl)phosphonic acid, dihydrate
  • ({[(2S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid dihydrate
  • ({[(2S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid--water (1/2)
  • 1-((S)-3-hydroxy-2-(phosphonomethoxy)propyl)cytosine dihydrate
  • cidofovir hydrate

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:59495
oboInOwl#hasDbXref
KEGG:D00273
DRON_00010000
83171

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:59495
oboInOwl#hasOBONamespace
chebi_ontology
generic_name
Cidofovir Dihydrate
oboInOwl#hasDbXref
KEGG:D00273
DRON_00010000
83171
oboInOwl#id
CHEBI:59495
rxcui
199388
product_type
BULK INGREDIENT
listing_expiration_date
20241231
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
INJECTION, SOLUTION
pharm_class
Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC]
route
INTRAVENOUS
marketing_start_date
20091221
package_marketing_start_date
27-NOV-23
active_ingredient_strength
375 mg/5mL
labeler_name
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
manufacturer_name
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
product_ndc
70225-1111
spl_id
f8870fdd-97bc-4c49-bde3-84ef1d397f44
active_ingredient_name
CIDOFOVIR
package_ndc
70225-1111-9
package_description
1 kg in 1 DRUM (70225-1111-9)
brand_name
CIDOFOVIR DIHYDRATE
brand_name_base
CIDOFOVIR DIHYDRATE
application_number
ANDA202501
unii
JIL713Q00N
spl_set_id
44966a7e-d777-40fb-956f-d0f31f737848
upc
0323155216318
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_36044
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_3696
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
Medication
http://purl.obolibrary.org/obo/DOID_0040086
Mechanism
http://purl.obolibrary.org/obo/DOID_0040086
Administration
http://purl.obolibrary.org/obo/DOID_0040086
has_treatment
http://purl.obolibrary.org/obo/DOID_6250
owl#annotatedSource
t252639
owl#someValuesFrom
t2909470