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Sapropterin

CHEBI:CHEBI_59560

Definition

A tetrahydropterin that is 2-amino-5,6,7,8-tetrahydropteridin-4(3H)-one in which a hydrogen at position 6 is substituted by a 1,2-dihydroxypropyl group (6R,1'R,2'S-enantiomer).

Chemical Information

Molecular Formula
C9H15N5O3
Molecular Mass
241.24710
Charge
0
SMILES
[H][C@@]1(CNc2nc(N)[nH]c(=O)c2N1)[C@@H](O)[C@H](C)O
InChI
InChI=1S/C9H15N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17)/t3-,4+,6-/m0/s1
InChIKey
FNKQXYHWGSIFBK-RPDRRWSUSA-N

Alternative Names

  • 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-pteridinone
  • 5,6,7,8-Tetrahydrobiopterin
  • (-)-(6R)-2-amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(3H)-pteridinone
  • (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one
  • (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin
  • (6R)-L-erythro-tetrahydrobiopterin
  • 6R-5,6,7,8-tetrahydrobiopterin
  • 6R-BH4
  • 6R-L-5,6,7,8-tetrahydrobiopterin
  • R-THBP
  • sapropterin
  • sapropterina
  • sapropterinum
  • tetrahydrobiopterin

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:59560
oboInOwl#hasDbXref
Wikipedia:Sapropterin
DRON_00010000
753340

Additional References

Wikipedia:Sapropterin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
POWDER, FOR SOLUTION
marketing_start_date
20131219
labeler_name
Solara Active Pharma Sciences Limited
spl_id
d7b2a60c-b7ac-4353-af15-8f0c5fafd172
package_ndc
49884-873-72
package_description
30 PACKET in 1 CARTON (49884-873-72) / 1 POWDER, FOR SOLUTION in 1 PACKET (49884-873-52)
application_number
ANDA210027
core#notation
CHEBI:59560
rxcui
2621237
active_ingredient_strength
100 kg/100kg
pharm_class
Phenylalanine Hydroxylase Activators [MoA]
package_marketing_start_date
14-DEC-07
manufacturer_name
BioMarin Pharmaceutical Inc.
active_ingredient_name
SAPROPTERIN DIHYDROCHLORIDE
unii
RG277LF5B3
spl_set_id
2e13a3b5-e4df-4d5c-9b26-02a7006a7c3e
upc
0349884873721
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Sapropterin
DRON_00010000
753340
oboInOwl#id
CHEBI:59560
oboInOwl#hasAlternativeId
CHEBI:64242
generic_name
Sapropterin dihydrochloride
brand_name
JAVYGTOR
brand_name_base
JAVYGTOR
product_ndc
49884-873
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_33295
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
has_treatment
http://purl.obolibrary.org/obo/DOID_9281
owl#annotatedSource
t252575
owl#someValuesFrom
t2996766