Discuss This Drug

clocortolone

CHEBI:CHEBI_59582

Definition

16alpha-Methylpregna-1,4-diene-3,20-dione bearing hydroxy substituents at the 11beta and 21 positions, fluorine at position 6 and chlorine at position 9. A medium potency corticosteroid, it is used as its 21-O-pivalate or caproate ester for the relief of inflammatory and pruritic (itching) skin disorders.

Chemical Information

Molecular Formula
C22H28ClFO4
Molecular Mass
410.90700
Charge
0
SMILES
[H][C@@]12C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(Cl)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C
InChI
InChI=1S/C22H28ClFO4/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-21(15,3)22(14,23)18(28)9-20(13,2)19(11)17(27)10-25/h4-5,7,11,13-14,16,18-19,25,28H,6,8-10H2,1-3H3/t11-,13+,14+,16+,18+,19-,20+,21+,22+/m1/s1
InChIKey
YMTMADLUXIRMGX-RFPWEZLHSA-N

Alternative Names

  • 9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methyl-1,4-pregnadien-3,20-dione
  • 9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
  • 9-chloro-6alpha-fluoro-16alpha-methyl-1,4-pregnadiene-11beta,21-diol-3,20-dione
  • clocortolona
  • clocortolone
  • clocortolonum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
21249
oboInOwl#hasDbXref
Wikipedia:Clocortolone
core#notation
CHEBI:59582

Additional References

Wikipedia:Clocortolone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
21249
oboInOwl#hasDbXref
Wikipedia:Clocortolone
oboInOwl#id
CHEBI:59582
core#notation
CHEBI:59582
rxcui
197520
product_type
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
CREAM
marketing_category
BULK INGREDIENT
pharm_class
Corticosteroid [EPC]
route
TOPICAL
active_ingredient_strength
10 g/10g
labeler_name
Farmabios S.p.A.
manufacturer_name
Dr. Reddy's Laboratories Inc
marketing_start_date
20140217
package_marketing_start_date
20140217
generic_name
Clocortolone Pivalate
active_ingredient_name
CLOCORTOLONE PIVALATE
product_ndc
26251-0002
spl_id
f188326e-08aa-301a-e053-2a95a90a621b
package_ndc
26251-0002-2
package_description
500 g in 1 BAG (26251-0002-2)
brand_name
clocortolone pivalate
brand_name_base
clocortolone pivalate
application_number
NDA017765
unii
QBL8IZH14X
spl_set_id
1eae193c-5cfd-5db1-344a-c951e2c9eff8
upc
0343598341750
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_59683
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect29560
owl#annotatedSource
t252547
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t581241