clomocycline
CHEBI:CHEBI_59589
Definition
Tetracycline in which the hydrogen at position 7 is substituted by chlorine and a hydrogen attached to the amide nitrogen is substituted by a hydroxymethyl group. A tetracyline antibiotic, it is used to treat acne, urinary tract infections, gum disease, and other bacterial infections such as gonorrhoea and chlamydia.
Chemical Information
- Molecular Formula
- C23H25ClN2O9
- Molecular Mass
- 508.90600
- Charge
- 0
- SMILES
- [H][C@@]12C[C@@]3([H])C(C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(=O)NCO)=C(O)[C@H]2N(C)C
- InChI
- InChI=1S/C23H25ClN2O9/c1-22(34)8-6-9-16(26(2)3)18(30)14(21(33)25-7-27)20(32)23(9,35)19(31)12(8)17(29)13-11(28)5-4-10(24)15(13)22/h4-5,8-9,16,27-28,30-31,34-35H,6-7H2,1-3H3,(H,25,33)/t8-,9-,16-,22-,23-/m0/s1
- InChIKey
- GJGDLRSSCNAKGL-KMVLDZISSA-N
Alternative Names
- (4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-N-(hydroxymethyl)-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
- chlormethylenecycline
- clomocyclina
- clomocycline
- clomocyclinum
Treatment Applications
-
gingival diseaseView Disease →
DOID:1483
-
dacryoadenitisView Disease →
DOID:950
-
submandibular adenitisView Disease →
DOID:4636
-
chronic dacryoadenitisView Disease →
DOID:949
-
chronic dacryocystitisView Disease →
DOID:9937
Drug Classification
-
tetracyclinesView Class →
CHEBI:26895
-
tertiary alpha-hydroxy ketoneView Class →
CHEBI:139592
-
t251364
-
t251852
-
t252322
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 21272
- oboInOwl#hasDbXref
- Patent:BE628142
- core#notation
- CHEBI:59589
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 21272
- oboInOwl#hasDbXref
- Patent:BE628142
- oboInOwl#id
- CHEBI:59589
- core#notation
- CHEBI:59589
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_48001
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_113888
- owl#annotatedSource
- t252255
- owl#someValuesFrom
- t682512