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Diflorasone

CHEBI:CHEBI_59750

Definition

The 16beta-analogue of flumethasone. It is used as the 17,21-diacetate as a topical anti-inflammatory and antipruritic in the treatment of various skin disorders.

Chemical Information

Molecular Formula
C22H28F2O5
Molecular Mass
410.45150
Charge
0
SMILES
[H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C
InChI
InChI=1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13-,14-,16-,17-,19-,20-,21-,22-/m0/s1
InChIKey
WXURHACBFYSXBI-XHIJKXOTSA-N

Alternative Names

  • (6alpha,11beta,16beta)-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
  • 6alpha,9-difluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
  • diflorasona
  • diflorasone
  • diflorasonum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Diflorasone
DRON_00010000
91311
core#notation
CHEBI:59750

Additional References

Wikipedia:Diflorasone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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oboInOwl#hasDbXref
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DRON_00010000
91311
oboInOwl#id
CHEBI:59750
product_type
BULK INGREDIENT
listing_expiration_date
20241231
marketing_category
BULK INGREDIENT
dosage_form
OINTMENT
route
TOPICAL
labeler_name
Innovida Pharmaceutique Corporation
marketing_start_date
19990514
generic_name
diflorasone diacetate
brand_name
psorcon
brand_name_base
psorcon
product_ndc
71800-009
application_number
ANDA076263
spl_id
727a87ee-8629-49f4-8550-bcf670037a8b
package_ndc
71800-009-60
RO_0000087
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core#notation
CHEBI:59750
rxcui
966820
pharm_class
Corticosteroid [EPC]
active_ingredient_strength
1 kg/kg
manufacturer_name
Innovida Pharmaceutique Corporation
package_marketing_start_date
19990514
active_ingredient_name
DIFLORASONE DIACETATE
package_description
1 TUBE in 1 CARTON (71800-009-60) / 60 g in 1 TUBE
unii
7W2J09SCWX
spl_set_id
0705869c-b801-4477-b8fe-e06b1cd37352
upc
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