Discuss This Drug

fondaparinux

CHEBI:CHEBI_61033

Definition

A synthetic pentasaccharide which, apart from the O-methyl group at the reducing end of the molecule, consists of monomeric sugar units which are identical to a sequence of five monomeric sugar units that can be isolated after either chemical or enzymatic cleavage of the polymeric glycosaminoglycans heparin and heparan sulfate.

Chemical Information

Molecular Formula
C31H53N3O49S8
Molecular Mass
1508.26300
Charge
0
SMILES
CO[C@H]1O[C@H](COS(O)(=O)=O)[C@@H](O[C@@H]2O[C@H]([C@@H](O[C@H]3O[C@H](COS(O)(=O)=O)[C@@H](O[C@@H]4O[C@@H]([C@@H](O[C@H]5O[C@H](COS(O)(=O)=O)[C@@H](O)[C@H](O)[C@H]5NS(O)(=O)=O)[C@H](O)[C@H]4O)C(O)=O)[C@H](OS(O)(=O)=O)[C@H]3NS(O)(=O)=O)[C@H](O)[C@H]2OS(O)(=O)=O)C(O)=O)[C@H](O)[C@H]1NS(O)(=O)=O
InChI
InChI=1S/C31H53N3O49S8/c1-69-27-9(33-85(48,49)50)13(37)17(6(74-27)3-71-88(57,58)59)76-31-22(83-91(66,67)68)16(40)21(24(81-31)26(43)44)79-29-10(34-86(51,52)53)19(82-90(63,64)65)18(7(75-29)4-72-89(60,61)62)77-30-15(39)14(38)20(23(80-30)25(41)42)78-28-8(32-84(45,46)47)12(36)11(35)5(73-28)2-70-87(54,55)56/h5-24,27-40H,2-4H2,1H3,(H,41,42)(H,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)/t5-,6-,7-,8-,9-,10-,11-,12-,13-,14-,15-,16+,17-,18-,19-,20+,21+,22-,23+,24-,27+,28-,29-,30-,31-/m1/s1
InChIKey
KANJSNBRCNMZMV-ABRZTLGGSA-N

Alternative Names

  • fondaparin
  • Natural heparin pentasaccharide
  • methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1->4)-beta-D-glucopyranuronosyl-(1->4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1->4)-2-O-sulfo-alpha-L-idopyranuronosyl-(1->4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:61033
DRON_00010000
321208
oboInOwl#hasDbXref
Wikipedia:Fondaparinux

Additional References

Wikipedia:Fondaparinux

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:61033
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
321208
oboInOwl#hasDbXref
Wikipedia:Fondaparinux
oboInOwl#hasAlternativeId
CHEBI:44566
oboInOwl#id
CHEBI:61033
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
INJECTION, SOLUTION
marketing_start_date
20090226
labeler_name
Apicore US LLC
generic_name
fondaparinux sodium
brand_name
Arixtra
brand_name_base
Arixtra
product_ndc
0781-3476
application_number
ANDA206918
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50249
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_145599
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_61038
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_106316
has_treatment
http://purl.obolibrary.org/obo/DOID_9477
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect29936
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_61038
owl#annotatedSource
t256067
owl#someValuesFrom
t629249
listing_expiration_date
20241231
route
SUBCUTANEOUS
spl_id
4c9b7e6e-ced7-4cd8-b3f7-dfb7322e3fbd
package_ndc
0781-3476-95
package_description
10 SYRINGE in 1 CARTON (0781-3476-95) / .8 mL in 1 SYRINGE (0781-3476-94)
rxcui
861366
package_marketing_start_date
26-FEB-09
manufacturer_name
Zydus Pharmaceuticals (USA) Inc.
active_ingredient_strength
10 mg/.8mL
active_ingredient_name
FONDAPARINUX SODIUM
unii
X0Q6N9USOZ
spl_set_id
dffbf7c9-495e-4a33-ac76-57b52f014fc2
upc
0370710151560
pharm_class
Factor Xa Inhibitors [MoA]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class