belinostat

CHEBI:CHEBI_61076

Definition

A hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.

Chemical Information

Molecular Formula
C15H14N2O4S
Molecular Mass
318.34800
Charge
0
SMILES
ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)Nc1ccccc1
InChI
InChI=1S/C15H14N2O4S/c18-15(16-19)10-9-12-5-4-8-14(11-12)22(20,21)17-13-6-2-1-3-7-13/h1-11,17,19H,(H,16,18)/b10-9+
InChIKey
NCNRHFGMJRPRSK-MDZDMXLPSA-N

Alternative Names

  • (2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]acrylamide
  • (2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide
  • belinostat
  • N-Hydroxy-3-(3-(phenylsulfamoyl)phenyl)prop-2-enamide
  • PXD101

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1543543
oboInOwl#hasDbXref
Wikipedia:Belinostat
core#notation
CHEBI:61076

Additional References

Wikipedia:Belinostat

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1543543
oboInOwl#hasDbXref
Wikipedia:Belinostat
oboInOwl#id
CHEBI:61076
core#notation
CHEBI:61076
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_61115
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_104080
has_treatment
http://purl.obolibrary.org/obo/DOID_6723
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect29972
owl#annotatedSource
t259488
owl#someValuesFrom
t3038377