Discuss This Drug

belinostat

CHEBI:CHEBI_61076

Definition

A hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.

Chemical Information

Molecular Formula
C15H14N2O4S
Molecular Mass
318.34800
Charge
0
SMILES
ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)Nc1ccccc1
InChI
InChI=1S/C15H14N2O4S/c18-15(16-19)10-9-12-5-4-8-14(11-12)22(20,21)17-13-6-2-1-3-7-13/h1-11,17,19H,(H,16,18)/b10-9+
InChIKey
NCNRHFGMJRPRSK-MDZDMXLPSA-N

Alternative Names

  • (2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]acrylamide
  • (2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide
  • belinostat
  • N-Hydroxy-3-(3-(phenylsulfamoyl)phenyl)prop-2-enamide
  • PXD101

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1543543
oboInOwl#hasDbXref
Wikipedia:Belinostat
core#notation
CHEBI:61076

Additional References

Wikipedia:Belinostat

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1543543
oboInOwl#hasDbXref
Wikipedia:Belinostat
oboInOwl#id
CHEBI:61076
core#notation
CHEBI:61076
rxcui
1543552
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
listing_expiration_date
20241231
dosage_form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
route
INTRAVENOUS
marketing_start_date
20140721
labeler_name
Curia New York, Inc.
manufacturer_name
Acrotech Biopharma Inc
active_ingredient_strength
500 mg/10mL
package_marketing_start_date
20140721
nui
N0000175071
pharm_class_epc
Histone Deacetylase Inhibitor [EPC]
pharm_class
Histone Deacetylase Inhibitors [MoA]
pharm_class_moa
Histone Deacetylase Inhibitors [MoA]
generic_name
Belinostat
brand_name
Beleodaq
brand_name_base
Beleodaq
product_ndc
65392-2509
application_number
NDA206256
spl_id
f54afb45-4160-53d2-e053-2a95a90aac09
active_ingredient_name
BELINOSTAT
package_ndc
65392-2509-0
package_description
20 kg in 1 DRUM (65392-2509-0)
unii
F4H96P17NZ
spl_set_id
2e8ef36b-71fa-4492-a16f-577d5f7d111d
upc
0372893002011
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_61115
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https://w3id.org/def/predibionto#has_drug_104080
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http://purl.obolibrary.org/obo/DOID_6723
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https://w3id.org/def/predibionto#has_side_effect29972
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t259488
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t3038377