Discuss This Drug

fingolimod

CHEBI:CHEBI_63115

Definition

An aminodiol that consists of propane-1,3-diol having amino and 2-(4-octylphenyl)ethyl substituents at the 2-position. It is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis. A prodrug, fingolimod is phosphorylated by sphingosine kinase to active metabolite fingolimod-phosphate, a structural analogue of sphingosine 1-phosphate.

Chemical Information

Molecular Formula
C19H33NO2
Molecular Mass
307.47080
Charge
0
SMILES
CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1
InChI
InChI=1S/C19H33NO2/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-22/h9-12,21-22H,2-8,13-16,20H2,1H3
InChIKey
KKGQTZUTZRNORY-UHFFFAOYSA-N

Alternative Names

  • 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol
  • fingolimod
  • fingolimodum
  • FTY-720
  • FTY720

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:63115
DRON_00010000
1012892
oboInOwl#hasDbXref
Wikipedia:Fingolimod

Additional References

Wikipedia:Fingolimod

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

route
ORAL
package_ndc
65015-834-61
package_description
100 kg in 1 DRUM (65015-834-61)
spl_id
13a21056-33f7-a068-e063-6294a90a0208
core#notation
CHEBI:63115
active_ingredient_strength
5 kg/5kg
active_ingredient_name
FINGOLIMOD LAURYL SULFATE
unii
J3HZQ9BE2S
spl_set_id
5434bd4a-2610-0e17-4f14-513ff1cbb822
upc
0372865257302
pharm_class_moa
Sphingosine 1-Phosphate Receptor Modulators [MoA]
pharm_class
Sphingosine 1-phosphate Receptor Modulator [EPC]
pharm_class_epc
Sphingosine 1-phosphate Receptor Modulator [EPC]
nui
N0000181815
rxcui
2045493
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
TABLET, ORALLY DISINTEGRATING
labeler_name
Cycle Pharmaceuticals Ltd
marketing_start_date
20100921
application_number
ANDA207933
product_ndc
0378-4525
manufacturer_name
Cycle Pharmaceuticals Ltd
package_marketing_start_date
21-SEP-10
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1012892
oboInOwl#hasDbXref
Wikipedia:Fingolimod
oboInOwl#id
CHEBI:63115
generic_name
Fingolimod hydrochloride
brand_name
TASCENSO ODT
brand_name_base
TASCENSO ODT
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_73416
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_63113
has_treatment
http://purl.obolibrary.org/obo/DOID_2377
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect30286
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_63113
owl#annotatedSource
t262916
owl#someValuesFrom
t3933241