Levofloxacin
CHEBI:CHEBI_63598
Definition
An optically active form of ofloxacin having (S)-configuration; an inhibitor of bacterial topoisomerase IV and DNA gyrase.
Chemical Information
- Molecular Formula
- C18H20FN3O4
- Molecular Mass
- 361.373
- Charge
- 0
- SMILES
- C[C@H]1COC2=C(N3CCN(C)CC3)C(F)=CC3=C2N1C=C(C(O)=O)C3=O
- InChI
- InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1
- InChIKey
- GSDSWSVVBLHKDQ-JTQLQIEISA-N
Alternative Names
- (-)-ofloxacin
- (-)-Ofloxacin
- (3S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid
- (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
- (S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid
- (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
- (S)-ofloxacin
- DR 3355
- DR-3355
- L-ofloxacin
- levofloxacin
- levofloxacine
- levofloxacino
- levofloxacinum
- Ofloxacin S-(-)-form
- S-(-)-ofloxacin
Drug Classification
-
quinolone antibioticView Class →
CHEBI:86324
-
fluoroquinolone antibioticView Class →
CHEBI:87211
-
t261922
-
t262510
-
t262591
-
t262605
-
t262870
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Levofloxacin
- DRON_00010000
- 82122
- core#notation
- CHEBI:63598
Additional References
Wikipedia:Levofloxacin
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Levofloxacin
- DRON_00010000
- 82122
- oboInOwl#id
- CHEBI:63598
- oboInOwl#hasAlternativeId
- CHEBI:6440
- generic_name
- LEVOFLOXACIN HEMIHYDRATE
- brand_name
- LEVOFLOXACIN
- brand_name_base
- LEVOFLOXACIN
- product_ndc
- 63323-355
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_59517
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_enantiomer_of
- http://purl.obolibrary.org/obo/CHEBI_46577
- package_ndc
- 58032-1006-0
- product_type
- BULK INGREDIENT
- dosage_form
- INJECTION, SOLUTION, CONCENTRATE
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- labeler_name
- YiChang HEC ChangJiang Pharmaceutical Co., Ltd.
- application_number
- ANDA200674
- package_description
- 10 TABLET, FILM COATED in 1 BOTTLE (80425-0007-4)
- route
- OPHTHALMIC
- spl_id
- 24c30337-b69f-3bcc-e063-6394a90a43aa
- marketing_start_date
- 20121110
- rxcui
- 1665519
- unii
- 6GNT3Y5LMF
- spl_set_id
- d98cf024-51fa-45a1-b247-da55aba88ca0
- manufacturer_name
- RPK Pharmaceuticals, Inc.
- listing_expiration_date
- 20241231
- core#notation
- CHEBI:63598
- pharm_class_epc
- Fluoroquinolone Antibacterial [EPC]
- pharm_class_cs
- Fluoroquinolones [CS]
- upc
- 0371205234072
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- package_marketing_start_date
- 01-OCT-05
- has_treatment
- http://purl.obolibrary.org/obo/DOID_0081455
- BFO_0000051
- http://purl.obolibrary.org/obo/CHEBI_7731
- owl#someValuesFrom
- t2991848
- owl#annotatedSource
- t262947
- active_ingredient_strength
- 40 kg/40kg
- active_ingredient_name
- LEVOFLOXACIN
- nui
- M0372253