Discuss This Drug

linezolid

CHEBI:CHEBI_63607

Definition

An organofluorine compound that consists of 1,3-oxazolidin-2-one bearing an N-3-fluoro-4-(morpholin-4-yl)phenyl group as well as an acetamidomethyl group at position 5. A synthetic antibacterial agent that inhibits bacterial protein synthesis by binding to a site on 23S ribosomal RNA of the 50S subunit and prevents further formation of a functional 70S initiation complex.

Chemical Information

Molecular Formula
C16H20FN3O4
Molecular Mass
337.34610
Charge
0
SMILES
CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(N2CCOCC2)c(F)c1
InChI
InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1
InChIKey
TYZROVQLWOKYKF-ZDUSSCGKSA-N

Alternative Names

  • linezolid
  • Linezolid
  • N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide
  • N-({(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
190376
oboInOwl#hasDbXref
Wikipedia:Linezolid
core#notation
CHEBI:63607

Additional References

Wikipedia:Linezolid

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

package_description
10 POUCH in 1 CASE (0409-4883-10) / 1 BAG in 1 POUCH / 300 mL in 1 BAG (0409-4883-03)
package_ndc
70771-1111-9
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
GRANULE, FOR SUSPENSION
marketing_start_date
20090520
labeler_name
Zhejiang Changhai Pharmaceuticals Co., Ltd.
application_number
NDA206473
product_ndc
58623-0129
listing_expiration_date
20241231
route
INTRAVENOUS
spl_id
369260a2-3528-44e4-aae4-a3191130462e
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
190376
oboInOwl#hasDbXref
Wikipedia:Linezolid
oboInOwl#id
CHEBI:63607
oboInOwl#hasAlternativeId
CHEBI:6477
generic_name
LINEZOLID
brand_name
Zyvox
brand_name_base
Zyvox
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_48001
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:63607
pharm_class
Oxazolidinone Antibacterial [EPC]
pharm_class_cs
Oxazolidinones [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
package_marketing_start_date
11-SEP-06
rxcui
1662280
manufacturer_name
Piramal Critical Care Inc.
active_ingredient_strength
200 mg/100mL
active_ingredient_name
LINEZOLID
unii
ISQ9I6J12J
spl_set_id
c401f1a8-cc37-461b-bfef-f2e156629bf8
nui
M0361132
upc
0359762130716
pharm_class_epc
Oxazolidinone Antibacterial [EPC]
has_treatment
http://purl.obolibrary.org/obo/DOID_401
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect30508
owl#annotatedSource
t262872
owl#someValuesFrom
t2988528