maraviroc
CHEBI:CHEBI_63608
Definition
A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4,4-difluorocyclohexanecarboxylic acid and the primary amino group of (1S)-3-[(3-exo)-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropylamine. An antiretroviral drug, it prevents the interaction of HIV-1 gp120 and chemokine receptor 5 (CCR5) necessary for CCR5-tropic HIV-1 to enter cells.
Chemical Information
- Molecular Formula
- C29H41F2N5O
- Molecular Mass
- 513.66550
- Charge
- 0
- SMILES
- CC(C)c1nnc(C)n1[C@H]1C[C@@H]2CC[C@H](C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccccc1
- InChI
- InChI=1S/C29H41F2N5O/c1-19(2)27-34-33-20(3)36(27)25-17-23-9-10-24(18-25)35(23)16-13-26(21-7-5-4-6-8-21)32-28(37)22-11-14-29(30,31)15-12-22/h4-8,19,22-26H,9-18H2,1-3H3,(H,32,37)/t23-,24+,25-,26-/m0/s1
- InChIKey
- GSNHKUDZZFZSJB-QYOOZWMWSA-N
Alternative Names
- 4,4-difluoro-N-{(1S)-3-[(3-exo)-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl}cyclohexanecarboxamide
- maraviroc
- maravirocum
Drug Classification
-
monocarboxylic acid amideView Class →
CHEBI:29347
-
triazolesView Class →
CHEBI:35727
-
organofluorine compoundView Class →
CHEBI:37143
-
azabicycloalkaneView Class →
CHEBI:38295
-
t262446
-
t262467
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:63608
- oboInOwl#hasDbXref
- Wikipedia:Maraviroc
- DRON_00010000
- 620216
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- core#notation
- CHEBI:63608
- rxcui
- 728225
- active_ingredient_strength
- 24.999 kg/24.999kg
- active_ingredient_name
- MARAVIROC
- unii
- MD6P741W8A
- spl_set_id
- d3a728e2-1866-462e-bfcc-5f3c9dd88794
- nui
- N0000175445
- pharm_class_epc
- CCR5 Co-receptor Antagonist [EPC]
- pharm_class
- Chemokine Co-receptor 5 Antagonists [MoA]
- pharm_class_moa
- Chemokine Co-receptor 5 Antagonists [MoA]
- upc
- 0372319025020
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- listing_expiration_date
- 20241231
- route
- ORAL
- package_marketing_start_date
- 24-SEP-19
- manufacturer_name
- A2A Integrated Pharmaceuticals
- spl_id
- d7917a7a-3248-7598-e053-2a95a90a2a90
- package_ndc
- 12828-0091-5
- package_description
- 15 kg in 1 DRUM (12828-0091-5)
- marketing_start_date
- 20231123
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Maraviroc
- DRON_00010000
- 620216
- oboInOwl#id
- CHEBI:63608
- generic_name
- MARAVIROC
- dosage_form
- POWDER
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- labeler_name
- n.v. Ajinomoto Omnichem s.a.
- brand_name
- SELZENTRY
- brand_name_base
- SELZENTRY
- product_ndc
- 12828-0091
- application_number
- NDA208984
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_59886
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect30516
- owl#annotatedSource
- t262925
- owl#someValuesFrom
- t3068577