Discuss This Drug

Misoprostol

CHEBI:CHEBI_63610

Definition

A diastereoisomeric mixture composed of approximately equal amounts of a double racemate of four of the sixteen possible diastereoisomers of methyl (13E)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate that is racemic prostaglandin E1 which is lacking the hydroxy group at position 15, but which has an additional hydroxy group at position 16. It is a synthetic prostaglandin E1 analogue, used in the treatment of gastric and duodenal ulcers. A weak abortifacient, it is also used for cervical ripening prior to surgical termination of pregnancy. The (11R,16S)-diastereoisomer is the pharmacologically active form.

Alternative Names

  • (+-)-methyl (1R,2R,3R)-3-hydroxy-2-((E)-(4RS)-4-hydroxy-4-methyl-1-octenyl)-5-oxocyclopentaneheptanoate
  • (11-alpha,13E)-(+-)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid methyl ester
  • Arthrotec
  • Cytotec
  • Methyl (+-)-11-alpha,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
  • misoprostol
  • misoprostolum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
42331
oboInOwl#hasDbXref
Wikipedia:Misoprostol
core#notation
CHEBI:63610

Additional References

Wikipedia:Misoprostol

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

package_description
1000 g in 1 BOTTLE (60592-234-10)
package_ndc
51927-0255-0
listing_expiration_date
20241231
route
ORAL
labeler_name
GenBioPro, Inc.
marketing_start_date
19861227
spl_id
23864ca5-37f4-8ff6-e063-6394a90a6c6b
rxcui
209177
manufacturer_name
GenBioPro, Inc.
package_marketing_start_date
29-JUL-20
unii
0E43V0BB57
spl_set_id
c4668066-3d67-487d-9071-f1e504f66499
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
42331
oboInOwl#hasDbXref
Wikipedia:Misoprostol
oboInOwl#id
CHEBI:63610
oboInOwl#hasAlternativeId
CHEBI:6952
brand_name
MISOPROSTOL
brand_name_base
MISOPROSTOL
generic_name
Misoprostol Dispersion
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
LIQUID
product_ndc
60592-234
application_number
ANDA216872
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50691
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_63705
core#notation
CHEBI:63610
active_ingredient_strength
50 kg/50kg
active_ingredient_name
MISOPROSTOL
nui
M0017811
upc
0342571253608
pharm_class_epc
Prostaglandin E1 Analog [EPC]
pharm_class
Synthetic [CS]
pharm_class_cs
Prostaglandins E, Synthetic [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_1873
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113040
owl#annotatedSource
t262983
owl#someValuesFrom
t3055482