Discuss This Drug

Nevirapine

CHEBI:CHEBI_63613

Definition

A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.

Chemical Information

Molecular Formula
C15H14N4O
Molecular Mass
266.29790
Charge
0
SMILES
Cc1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12
InChI
InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)
InChIKey
NQDJXKOVJZTUJA-UHFFFAOYSA-N

Alternative Names

  • 11-cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
  • NEV
  • nevirapine
  • Nevirapine
  • NVP
  • Viramune

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Nevirapine
DRON_00010000
53654
core#notation
CHEBI:63613

Additional References

Wikipedia:Nevirapine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
ORAL
marketing_start_date
20240117
spl_id
22e69094-c719-4109-b238-c6234a906d68
package_ndc
53104-7623-1
package_description
25 kg in 1 DRUM (53104-7623-1)
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Nevirapine
DRON_00010000
53654
oboInOwl#id
CHEBI:63613
oboInOwl#hasAlternativeId
CHEBI:7546
generic_name
NEVIRAPINE ANHYDROUS
brand_name
NEVIRAPINE
brand_name_base
NEVIRAPINE
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
SUSPENSION
labeler_name
Mylan Pharmaceuticals Inc.
product_ndc
53104-7623
application_number
NDA020933
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_53756
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:63613
rxcui
213405
active_ingredient_strength
50 kg/50kg
pharm_class_moa
Non-Nucleoside Reverse Transcriptase Inhibitors [MoA]
pharm_class
Non-Nucleoside Analog [EXT]
nui
N0000009948
manufacturer_name
Mylan Pharmaceuticals Inc.
package_marketing_start_date
21-JUN-96
pharm_class_epc
Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]
active_ingredient_name
NEVIRAPINE
unii
99DK7FVK1H
spl_set_id
5ec05500-6333-4bd0-ac83-464fad0d5162
upc
0342571131609
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect30582
owl#annotatedSource
t262976
owl#someValuesFrom
t3000420